Progress in diagnosis and treatment of chronic cough.docVIP

 PAGE \* MERGEFORMAT 14 Progress in diagnosis and treatment of chronic cough Chronic cough (chronic persistent cough, CPC) is a respiratory disease, one of the most common chief complaint is defined as cough lasting more than three weeks, after examination failed to find significant lung disease. Since many patients with only symptoms are cough, check the etiology is difficult to find objective evidence, often delay in diagnosis, since the anatomy of chronic cough Irwin proposed diagnostic procedures, and continuously improve upon after, CPC’s cause diagnosis rate to 90% or more, and there have been The new cause was found [1]. An etiology and pathogenesis of The cause of the relatively consistent with cough variant asthma (cough variant asthma, CVA), postnasal drip syndrome (postnasal drip syndrome, PNDS), gastroesophageal reflux (gastro-esophageal reflux, GER), eosinophilic bronchial inflammation (eosinophilic bronchitis, EB), etc., there are scholars of drugs (such as angiotensin-converting enzyme inhibitor)-induced cough and psychogenic cough listed as well. Multi-center prospective study shows that chronic cough and 32% ~ 82% for the single-factor, 18% ~ 62% for multi-factor [2]. Abroad, the literature [3] of 1258 cases of statistical analysis showed that the cause of chronic cough, chronic rhinitis related cough, accounting for 34% of the first, including some, including sinusitis, followed by 25% for non-typical asthma, esophageal lesions by 20%. 1.1 PNDS Generally refers to the nose and paranasal sinus secretions after the drip, repeated inhalation, to stimulate the throat caused by partial reflection of chronic cough, including the various causes, such as chronic rhinitis, allergic rhinitis, vasomotor rhinitis, sinusitis, nasal polyps and so on. Therefore, independence is not a disease, and known as postnasal drip syndrome. Nasal mucosa may have a similar with the lower respiratory tract inflammation, and its sensory nerve endings containing airwa