Rapid Identification of chemical methods of gemfibrozil capsules.doc

 PAGE \* MERGEFORMAT 7 Rapid Identification of chemical methods of gemfibrozil capsules [Abstract] Objective To identify chemical method is fast gemfibrozil capsules. Methods Gemfibrozil soluble in ethanol made from the physical nature of the solution, because of its structure with the aryl acid functional groups with 50% nitric acid reaction of colored material (green) in combination with the reaction by TLC to identify Kyrgyzstan non-Luo Qi Capsules. The results with 50% nitric acid reaction of the green material, you can identify the authenticity of Gemfibrozil; by thin-layer chromatography can be distinguished Gemfibrozil Capsules and other similar drugs difference. Conclusion The combination of thin-layer chromatography chemical methods can not only quickly identify Gemfibrozil capsules of authenticity, and can be Gemfibrozil Capsules and other similar drugs make that distinction. [Keywords:] Chemical method; rapid identification; Gemfibrozil; color reaction; thin-layer chromatography Gemfibrozil (Gemfibrozil) can inhibit the decomposition of adipose tissue, reducing the liver free fatty acid levels, thereby reducing hepatic synthesis of triglycerides; also inhibits the synthesis of apolipoprotein B to reduce the very low density lipoprotein levels, lower blood in the cholesterol. Gemfibrozil has reduced very low density lipoprotein in blood, and the role of triglycerides, use of this drug can reduce the incidence of coronary heart disease and mortality. Its structural formula shown in Figure 1. Gemfibrozil capsule is a common lipid-lowering drugs on the market because the drug market price is relatively high, so are more counterfeit drugs; using this method can quickly identify the authenticity of Gemfibrozil by chemical method is rapid identification of Kyrgyzstan fibrozil not been reported in the literature study. This paper studies the chemical method is rapid identification of Gemfibrozil method. An experimental material 1.1 Thin plate apparat