Reconstruction of bone tissue engineering in jaw defects in the research.docVIP

 PAGE \* MERGEFORMAT 20 Reconstruction of bone tissue engineering in jaw defects in the research Bone tissue defects can be caused by a variety of reasons, including cancer, inflammation, trauma and other reasons, of which the tumor of the bone defect is most common bone tumor defects of future repair and reconstruction of Surgical Oncology in one direction [1]. Oral malignant tumors often lead to mandibular or maxillary defects, repair methods are commonly used autologous bone, allogeneic bone and artificial materials, etc., but these repair methods can not meet the clinical needs. More recently, tissue engineering with this emerging science and technology, the rise can take advantage of this technology has reached the bone reconstruction and to meet the clinical needs. In this paper, oral cancer and the relationship between the mandibular defect, bone tissue engineering re-key the content and progress of the repair of mandibular defects are reviewed. An oral cancer and its complications after mandibular defects 1.1 Oral mandibular defects after tumor operation Oral and Maxillofacial has a rich lymphatic systems, oral cancer, are generally a violation of mandibular periosteum. Sudhir on 22 cases of oral cancer research is an infringement of the mandible, respectively, X-ray, CT examination, 21 cases were found in violation of the mandible, and with postoperative histology contrast, the positive rate is consistent with [2] . Tsuchimochi such as using 99mTc  MDP bone scan revealed a tumor of the mandible caused by a violation of cancellous bone [3]. Therefore, proceeding from the principle of tumor surgery, the mandible must be removed, is bound to cause mandibular defects. 1.2 Complications of mandibular defects Mandibular defects not only affect the facial beauty, more importantly is that it can cause, such as speech, swallowing, breathing and other functions obstacles. McConnel, etc. right after mandibular resection patients, oropharyngeal swallow eff