Scorpion dragon bone powder preparation and quality control.docVIP

 PAGE \* MERGEFORMAT 9 Scorpion dragon bone powder preparation and quality control Author: Liang Chen Fang Xiao Ping Liwen Shi Chun-Xu Yang [Abstract] Objective To prepare the scorpion dragon bone powder and the establishment of quality control methods. Method of preparation of scorpion dragon bone powder, using high performance liquid chromatography (HPLC) determination of scorpion Long Bone Powder Dracorhodin content. The results of the preparation for various tests are in line with scorpion dragon bone powder quality standard of the relevant provisions; dracorhodin at 9.59 ~ 47.94 mg * L-1 concentration range of linear relationship between peak area and the concentration of a good correlation coefficient r = 0.999 6, Canadian sample average recovery was 99.86% (RSD = 0.96%). Conclusion scorpion dragon bone powder preparation process is simple, stable quality, quality control method is feasible. [Keywords:] scorpion dragon bone powder; preparation; Quality Control Scorpion dragon bone powder is the 4th Affiliated Hospital of Guangxi Medical University in scientific research based on independent research and development of the powder, the preparation has been autonomous production of the Food and Drug Administration approval of the symbol (GUI pharmacists word: 20,060,003), with blood circulation , reduces swelling, pain, continued reinforcement of the effectiveness of bone and clinical for the treatment of bruises, closed fracture, etc. curative effect. Now its preparation methods and quality control report is as follows. An apparatus and materials Shimadzu LC  10Avp performance liquid chromatography (LC  10AT pump, SPD  10Avp detector, CBM  102 data processor, CS  Light chromatography data workstations); dracorhodin perchlorate reference substance (Chinese medicine Biological Products, Lot :0811-200203, 20 mg / sticks, content: 100%); thin-layer chromatography using silica gel G (Qingdao Silica gel desiccant waves factory); scorpion dragon b