Screening of traditional Chinese medicine to kill Entamoeba gingivalis_0.docVIP

 PAGE \* MERGEFORMAT 10 Screening of traditional Chinese medicine to kill Entamoeba gingivalis Of: Liangyu Fen, Weijun Bin, Li Yi Yi, Haiying, Xia Yun Chen [Abstract] Objective berberine and other 12 kinds of Chinese medicine to kill Entamoeba gingivalis (Entamoeba gingivalis, Eg). Methods 2 50% were prepared traditional Chinese medicine extract and water extract of ethanol extract, using the same concentration in vitro Entamoeba gingivalis experiments, drug effects observed by light microscopy the morphological changes of Entamoeba gingivalis after the initial screening strong insecticidal drugs. and then have a strong insecticidal effect of the drug, and further diluted to different concentrations screening. The results of water extracts of pomegranate peel, water extract of Artemisia annua, Treats ethanol and water extract of Coptis show a clear role of anti-Eg. When the time dilution of 1:32, only the water extract of Artemisia annua 18h is used to kill all the parasites, while the other extracts were not within two days to kill all the worms. Conclusions are filtered in the 12 kinds of Chinese medicine, the killing effect of aqueous extract of Artemisia annua best. [Keywords:] Entamoeba gingivalis; medicine screening; insecticidal effect Entamoeba gingivalis (Entamoeba gingivalis, Eg) is a single cell of the animal, is a common human parasite, the main parasite in the human body in the mouth, can cause gingivitis and periodontitis and other oral diseases. Some scholars study showed that metronidazole azole and tinidazole is better to kill Eg [1], but clinical practice shows that metronidazole and tinidazole, can cause severe gastrointestinal reactions, and even toxic side effects such as teratogenic and carcinogenic. In order to find new anti- Eg drugs, the paper selected insecticidal, anti-inflammatory and antibacterial effects of 12 kinds of traditional Chinese medicine [2 ~ 4], respectively, was observed in vitro killing experiments Eg. now