Surgical approach of type 2 diabetes and its mechanism.docVIP

 PAGE \* MERGEFORMAT 29 Surgical approach of type 2 diabetes and its mechanism Of: Zhuheng Liang, Xumiao Jun, Jiang Fei Zhao, Zheng wind [Keywords:] Type 2 diabetes; surgical approach; therapeutic mechanism Type 2 diabetes mellitus (T2DM) from the surgical treatment of obesity surgery (bariatric surgery). The early study found that obesity associated with type 2 diabetes patients receiving obesity surgery, blood sugar well controlled, or even completely out of diabetes medication; and these patients before blood is returned to the normal range early after surgery (lt;1 week), long before weight loss [1-2], showed that obese patients with type 2 diabetes, blood glucose returned to normal after surgery there in addition to weight loss more important than the cause. This has led to great interest doctors. From the beginning of the 20th century, 90s, obesity surgery in patients with type 2 diabetes is widely applied in the original method of obesity surgery on the basis of there are some new surgical approach. In recent years, “diabetes surgery” Dr. Rubino term well-known experts in the literature has gradually begun to use, in order to facilitate the description, this review will use the term “diabetes surgery” is, involving “Diabetes Surgery “is, are specifically” type 2 diabetes surgery. “surgery now associated with type 2 diabetes and its machines to produce a surgical review. 1 2 diabetes overview of surgical treatment of the underlying mechanisms The reason why type 2 diabetes can be surgical treatment, and the secretion of gastrointestinal tract, and insulin-related hormone changes after surgery is related to these hormones and insulin constitutes a “gut - insulin-axis” (enteroinsular axis). In addition to the members of the axis insulin, it also includes cholecystokinin, gastric inhibitory peptide (gastric inhibitory peptide, GIP), glucagon-like peptide-l (glucagon-like peptide 1, GLP-1), and ghrelin, leptin (leptin) and ethylene nitrile (adi