循证医学方法研究氟西汀与帕罗西汀治疗抑郁症的成本-效果.pdfVIP

·药物经济学· 主持人:胡替联杨莉陈文刘宝 主持人按:杜彪撰写的《循证医学方法研究氟尚汀与帕罗西汀治疗抑郁痒的成本一效采》一义，通过汇总相同设计的临床随机 对照研究，计算了 2 种药物治疗抑郁症的临床疗效及其药品费用，分析了成本…效采比率和增量成本…效果比卒，对于运用药物经 济学许价研究中的模拟分析方法具有一定参考价值。 循证医学方法研究氛西汀与帕罗西汀治疗抑郁症的成本一效果 杜 彪古(重庆三峡精神卫生中心，重庆市 404000) 中圄分类号 R956 文献标识码 C 文章编号 1001-0408(2005)17←1309 一 02 摘 要 阔的:评价氟西汀与帕罗西汀治疗抑郁症的成本一效泉。方法:采用循证医学方法收集鼎西汀与帕罗西汀治疗抑郁症的临 床资料，应用药物经济学的成本一效采分析法进行分析。结果:氟西汀与帕罗西汀治疗抑郁痪的治愈率分别为 36.30% 、 58.73% j 成本一效果比分别为 14.13、 9.73; 后者相对于前者的增量成本一效采比为 2.60 结论:帕罗西汀治疗抑郁症的成本一效采优于氟 0 西?丁。 ~rj 抑郁症;成本?效采分析 关键词 循证医学;氟西汀;帕罗西 Cost - effectiveness Analysis on Fluoxetine and Paroxetine in the Treatment of Depressive Disorder by Ev- idence … based 岛1:edicine 岛1:ethod DU Biao (Chongqing 丁hree Gorges Mental Health Center ,Chongqing 404000 , China) ABSTRACT OBJECTIVE: To evaluate the cost - effectiveness of fluxetine and paroxetine in the treatment of depressive disorders. METHODS: The clinical data of fluxetine and paroxetine in the treatment of depressive disorders were co l!ected by evidence - based medicine method and which were evaluated by cost - effectiveness analy日is in pharmacoeconomic5. RE- SULTS: The cur巳 rates of fluxetine and paroxetine in the treatment of depressive disorders were 36.30% and 58.73% , re- spectively ,and the cost - effectiven巳5S ratios of which wer巳 14.13 and 9.73 , respectively. The incremental cost - effectiven巳ss ratio of the latter vs. the former was 2.60. CONCLUSION: 丁he cost - effectiveness of paroxetine is 日uperior to fluxetine in the treatment of depr巳ssive disorders. KEY WORDS Evidence - based medicine j Fluoxetine; Paroxetine; Depressive disorder; Cost … effectiveness analysis 抑郁症是l临床最常见的精神疾病，世界卫生组织 (WHO)