持续不卧床腹膜透析患者亚临床甲状腺功能减退与左心室收缩功能关系的研究.pdfVIP

第 34 卷第6 期 安徽医学 739 2013 年6 月 Anhui Medical Journal 持续不卧床腹膜透析患者亚临床甲状腺功能减退 与左心室收缩功能关系的研究 丁士新郭长策 [摘要] 目的 对持续不卧床腹膜透析(CAPD)患者中亚临床甲状腺功能减退(SCH)和左心室收缩功能之间的关系进行研究。 方 法 采用横断面研究连续选取透龄超过3 个月的 CAPD 患者51 例，收集其人口学指标、临床及实验室数据。对SCH 和左心室收缩功能之 间的关系进行Logistic 回归分析。 结果 51 例 CAPD 患者中，并发 SCH 者 14 例(27.459串)。经Logistic 回归分析，校正年龄、合并糖尿病 者、血清清蛋白和 CRP 后，发现亚临床甲减(伊=-0.361 ，P=O.∞8)和 CRP 升高(严=0.378 ，1=0.011 )均是 CAPD 患者左心室收缩功能下降的 独立危险因京嗡 结论在CAPD 患者中，SCH 和左心室收缩功能下降存在独立相关性。 [关键词] 持续不卧床腹膜透析;亚临床甲状腺功能减退;左心室收缩功能 doi: 1 0.3969/j.issn.l∞0-0399.2013.06.024 Association between subclinical hypothyroidism and left ventricle systolic fuoction in patients with continuous ambulatory peri- ton姐1 dialysis Ding Shixin , Guo Changce Department of Nephrology , the PLA Naη Anqing Hospital ,Anqing 246003 , China [Abstract] Objective To study the association between subclinical hypothyroidism(SCH) and left ventricle systolic functi佣 in patients with continuous ambulatory peritoneal dialysis (CAPD). Methods All 51 CAPD patients were enrolled in this cross-sectional study. The ba- sic demographic characteristics , clinical and laboratory data of the patients were collected. Multivariable logistic regression me血。d was used to evaluate the assocÏation between SCH and the left ventricle systolic function. Results Among 51 CAPD patients , 14 cases(27 ,45%) were wi出 SCH. After adjusting for age , combined with diabetes mellitus , serum albumin and CRP ,SCH and increased CRP was independent risk factor with decresed LVEF (自=- 0.361 ,P =0.∞8 andß= 0.378 ,P =0.011). Conclusionηle study su昭ests that subclinical hypothyroidism is com- mon and might be independent correlate wi由 LVEF. [Key words] Continuous ambulatory peritoneal dialysis; Subclinical hyp