基于核壳式量子点CdSe-PDT光漂白规律的实验研究.docVIP

基于核壳式量子点CdSe-PDT光漂白规律的实验研究.doc

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基于核壳式量子点CdSe-PDT光漂白规律的实验研究

Hans Journal of Biomedicine 生物医学, 2012, 2, 6-10 /10.12677/hjbm.2012.21002 Published Online January 2012 (/journal/hjbm) Experimental Research on the Photobleaching Mechanism of PDT Based QDs-CdSe* Jian Wang , Dongxiang Hu , Jieguan Deng , Kangqiang Huang , Jianwen Xiong 1 1 2 1 1# 1 Laboratory of Quantum Information Technology, School of Physics and Telecommunication Engineering, South China Normal University, Guangzhou 2 Institute of Physics, Lanzhou University, Lanzhou # Email: @163.com, jwxiong@ Received: Sep. 30th, 2011; revised: Nov. 12th, 2011; accepted: Nov. 14th, 2011. Abstract: With the development of the basic research of photodynamic therapy (PDT), photosensitizer photobleaching has become a highly focused area of research within PDT in recent years. In this paper, the photobleaching mechanism of quantum dots in the FBS solution and HL60 cell solutions with oxygen substrate were investigated by the method of theoretical derivation. The results demonstrated that the photobleaching in the single solution was corresponded with the first order kinetics while the photobleaching in the complex solution was corresponded with the second order kinetics. The curve and rate of CdSe photobleaching were obtained by determining the vis absorption spectrum of the CdSe and using of the Beer. Additionally, the photobleaching properties of quantum dot (CdSe) whose theoretical derivation can be confirmed by our experiment were gained. Keywords: Photodynamic Therapy (PDT); Quantum Dots (QDs); CdSe; Photobleaching; HL60 cells 基于核壳式量子点 CdSe-PDT光漂白规律的实验研究* 王 健,胡冬香,邓解关,黄康强,熊建文 1# 1 1 2 1 1 2 广东省高等学校量子信息技术重点实验室,华南师范大学物理与电信工程学院,广州 兰州大学物理系,兰州 Email: @163.com, jwxiong@ # 收稿日期:2011年 9月 30日;修回日期:

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