- 1、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。。
- 2、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
- 4、该文档为VIP文档,如果想要下载,成为VIP会员后,下载免费。
- 5、成为VIP后,下载本文档将扣除1次下载权益。下载后,不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后,您将拥有八大权益,权益包括:VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传,每下载1次, 网站将根据用户上传文档的质量评分、类型等,对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
Apelin Serum Level in Egyptian Patients with Chronic Hepatitis C英文文献资料
HindawiPublishingCorporation
MediatorsofIn?ammation
Volume2011,ArticleID703031,7pages
doi:10.1155/2011/703031
ResearchArticle
ApelinSerumLevelinEgyptianPatientswithChronicHepatitisC
HalaO.El-Mesallamy, NadiaM.Hamdy, HananH.Rizk, andAbdel-RahmanEl-Zayadi
1 1 1 2
1
2
BiochemistryDepartment,FacultyofPharmacy,AinShamsUniversity,Abassia,Cairo11566,Egypt
TropicalMedicineDepartment,FacultyofMedicine,AinShamsUniversity,Cairo11566,Egypt
CorrespondenceshouldbeaddressedtoNadiaM.Hamdy,nadiahamdy@
Received8May2011;Revised8July2011;Accepted25August2011
AcademicEditor:GiamilaFantuzzi
Copyright?2011HalaO.El-Mesallamyetal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttribution
License,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperly
cited.
Objective.Highlightingtheapelinsystemwouldpresentanewtherapeutictargetforliverdisease.Apelin;endogenousligandfor
theorphanreceptorAPJ,wasrecentlysuggestedtobeassociatedwith?brosisprogressionandcirrhosisinadditiontoinsulin
resistance(IR)andin?ammation.Thepresentstudywasconducted toevaluatebloodapelinlevelchangesamong73chronic
hepatitisC(CHC)Egyptianpatientsandifassociatedwithbodymassindex(BMI),IR,andtumornecrosisfactor-alpha(TNF-
α).Serumapelinlevelsweresigni?cantlyhigherinpatientswithCHCwithmedianvalue(3.25)whencomparedwithcontrols
(1.11),atP0.0001,withsigni?cantapelinvariationsamongasymptomaticcarriers(ASC),?brosis,andcirrhosispatients,and
alsoamongobeseandnonobesepatients.MultipleregressionanalysisdepictedthatBMI,triglycerides,andtotalcholesterolwere
independentcorrelationfactorstoapelinlevels,whereasTNF-αwasfoundtobesigni?cantlynegativelycorrelatedtoadjusted
apelininCHCpatients(r = ?0.5944,P 0.0001).IRwaspositivelycorrelatedtoadjustedapelininCHCpatients(r =0.2663,
P0.05).Conclusion.ApelinlevelvariesamongstagesofCHC,whichmaycontributeto?brosisprogression.Inaddition,obesity
andIRcouldactascomorbidfacto
您可能关注的文档
- Analytical Solution of Two Extended Model Equations for Shallow Water Waves By Adomian’S Decomposition Method英文文献资料.doc
- Analyzing the Dynamics of a Rumor Transmission Model with Incubation英文文献资料.doc
- Analyzing Spur-Distorted Impedance Spectra for the QCM英文文献资料.doc
- Analyzing the Diverging Diamond Interchange Using Discrete Event Simulation英文文献资料.doc
- Anaphylactoid Shock with Infusion of 5% Albumin in a Patient under General Anesthesia英文文献资料.doc
- Analyzing “Homotopy Perturbation Method for Solving Fourth-Order Boundary Value Problem”英文文献资料.doc
- Anaphylaxis to Skin Prick Testing in a 29-Year-Old Woman英文文献资料.doc
- Anaplasma phagocytophilum and Anaplasma marginale Elicit Different Gene Expression Responses in Cultured Tick Cells英文文献资料.doc
- Analyzing an UWB Bandpass Filter for High Power Applications Using Rectangular Coaxial Cables with Square Inner Conductors英文文献资料.doc
- Anaplastic Thyroid Cancer A Review of Epidemiology, Pathogenesis, and Treatment英文文献资料.doc
- AOD Trends over Megacities Based on Space Monitoring Using MODIS and MISR英文文献资料.doc
- Apelin-12 improves metabolic and functional recovery of rat heart after global ischemia英文文献资料.doc
- Antiviral and Virucidal Activities of N -Cocoyl-L-Arginine Ethyl Ester英文文献资料.doc
- Aperture Coupled Microstrip Antenna for Dual-Band英文文献资料.doc
- Aperture Field Estimation in Waveguide for Non-Sinusoidal Periodic Excitation英文文献资料.doc
- Apocynin Molecular Aptitudes英文文献资料.doc
- APOE and FABP2 Polymorphisms and History of Myocardial Infarction, Stroke, Diabetes, and Gallbladder Disease英文文献资料.doc
- Apocynin Improves Insulin Resistance through Suppressing Inflammation in High-Fat Diet-Induced Obese Mice英文文献资料.doc
- ApoE Polymorphism Is Associated With C-Reactive Protein in Low-HDL Family Members and in Normolipidemic Subjects英文文献资料.doc
- Apoptosis and Redistribution of the Ro Autoantigen in Balbc Mouse Like in Subacute Cutaneous Lupus Erythematosus英文文献资料.doc
最近下载
- 《应用文写作》高职完整全套教学课件.pdf
- 人教版二年级上册数学全册教学设计(配2025年秋新版教材).docx
- 路灯维修工考试题库单选题100道及答案.docx VIP
- TDZJN 80-2022 数据中心用锂离子电池设备产品技术标准.docx
- 2025年教科版一年级《科学》上册全册教案 .pdf VIP
- 唱天瑶 课件接力版音乐五年级上册(共11张PPT)(含音频+视频).pptx VIP
- 数字化驱动下的智慧家庭医生服务报告.pdf VIP
- [工程科技]MODFLOW用户手册中文版.doc
- 苏教版小学一年级数学下学期综合检测试卷 附解析.pdf VIP
- 矿山排水工培训课件视频.pptx VIP
文档评论(0)