Assessment of depth of anesthesia using principal component analysis英文文献资料.docVIP

J. Biomedical Science and Engineering, 2009, 2, 9-15 9 Assessment of depth of anesthesia using principal component analysis Mina Taheri , Behzad Ahmadi , Rassoul Amirfattahi and Mojtaba Mansouri 1 2 3 4 1,2,3 Digital Signal Processing Research Lab, Department of Electrical and Computer Engineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran Medical Image and Signal Processing Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. Correspondence should be addressed to Mina Taheri (mh.taheri@ec.iut.ac.ir) 1,2,3,4 Received June 9 , 2008; revised October 12 , 2008; accepted November 13 , 2008 th th th ABSTRACT body temperature, tearing, sweating and heart rate [1], even though these signals are affected indirectly by an- esthetic agents. On the other hand, these agents have significant effects on the electroencephalogram (EEG) waveform. A new approach to estimating level of uncon- sciousness based on Principal Component Analysis (PCA) is proposed. The Electroen- cephalogram (EEG) data was captured in both Intensive Care Unit (ICU) and operating room, using different anesthetic drugs. Assuming the central nervous system as a 20-tuple source, window length of 20 seconds is applied to EEG. The mentioned window is considered as 20 A large amount of information can be extracted from EEG waveform based on different signal processing methods. Ability of this information to predict DOA de- pends on the variation of its value in different levels of anesthesia. In general, the goal is to produce a unit-less EEG-based index that monotonically quant