Bacterial Vaginosis and the Natural History of Human Papillomavirus英文文献资料.docVIP

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Bacterial Vaginosis and the Natural History of Human Papillomavirus英文文献资料.doc

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Bacterial Vaginosis and the Natural History of Human Papillomavirus英文文献资料

HindawiPublishingCorporation InfectiousDiseasesinObstetricsandGynecology Volume2011,ArticleID319460,8pages doi:10.1155/2011/319460 ResearchArticle BacterialVaginosisandtheNaturalHistoryof HumanPapillomavirus CarolineC.King, 1 DeniseJ.Jamieson, JeffreyWiener, SusanCu-Uvin, RobertS.Klein, 1 1 2 3 KeertiV.Shah, andJackD.Sobel 6 AnneM.Rompalo, 4 5 1 DivisionofReproductiveHealth,NationalCenterforChronicDiseasePreventionandHealthPromotion, CentersforDiseaseControlandPrevention,NCCDPHP,DRH,4770BufordHighway,MailstopK-34,Atlanta,GA30341,USA DepartmentofObstetricsandGynecology,AlpertMedicalSchoolofBrownUniversity,Providence,RI02912,USA DepartmentofMedicine,MountSinaiSchoolofMedicine,NewYork,NY10029,USA DivisionofInfectiousDiseases,SchoolofMedicine,JohnsHopkinsUniversity,Baltimore,MD21205,USA DepartmentofMolecularMicrobiologyandImmunology,JohnsHopkinsBloombergSchoolofPublicHealth,Baltimore, MD21205,USA 2 3 4 5 6 DivisionofInfectiousDiseases,WayneStateUniversitySchoolofMedicine,Detroit,MI48201-1998,USA CorrespondenceshouldbeaddressedtoCarolineC.King,ccking@ Received6May2011;Accepted7June2011 AcademicEditor:GregoryT.Spear Copyright?2011CarolineC.Kingetal. This is an open access article distributed under the Creative Commons Attribution License,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperly cited. Objective.Toevaluateassociationsbetweencommonvaginalinfectionsandhumanpapillomavirus(HPV).StudyDesign .Data fromupto15visitson756HIV-infectedwomenand380high-riskHIV-uninfectedwomenenrolledintheHIVEpidemiology ResearchStudy(HERS)wereevaluatedforassociationsofbacterialvaginosis,trichomoniasis,andvaginalCandidacolonization withprevalentHPV,incidentHPV,andclearanceofHPVinmultivariateanalysis.Results.Bacterialvaginosis(BV)wasassociated withincreasedoddsforprevalent(aOR=1.14,95%CI:1.04,1.26)andincident(aOR=1.24,95%CI:1.04,1.47)HPVandwith delayedclearanceofinfection(aHR=0.84,95%CI:0.72,