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Basal Cell Carcinoma 10 Years of Experience英文文献资料
HindawiPublishingCorporation
JournalofSkinCancer
Volume2011,ArticleID476362,5pages
doi:10.1155/2011/476362
ClinicalStudy
BasalCellCarcinoma:10YearsofExperience
EmanueleCigna,MauroTarallo,MicheleMaruccia,ValentinaSorvillo,
AlessiaPollastrini,andNicolo`Scuderi
DepartmentofPlasticandReconstructiveSurgery,PoliclinicoUmbertoI,00161Rome,Italy
CorrespondenceshouldbeaddressedtoEmanueleCigna,emanuelecigna@
Received27August2010;Revised15October2010;Accepted1November2010
AcademicEditor:DanielaMassi
Copyright?2011EmanueleCignaetal. This is an open access article distributed under the Creative Commons Attribution
License,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperly
cited.
Introduction.Basalcellcarcinoma(BCC)isalocallyinvasivemalignantepidermaltumour.Incidenceisincreasingby10%peryear;
incidenceofmetastasesisminimal,butrelapsesarefrequent(40%–50%).ThecompleteexcisionoftheBCCallowsreductionof
relapse.MaterialsandMethods.Thestudycohortconsistsof1123patientsunderwentsurgeryforbasalcellcarcinomabetween1999
and2009.Patientandtumorcharacteristicsrecordedare:age;gender;localization(headandneck,trunk,andupperandlower
extremities),tumorsize,excisionalmarginsadopted,andrelapses.Results.Thestudyconsideredagroupof1123patientsa?ected
bybasalcellcarcinoma.Relapsesoccurredin30cases(2,67%),27outof30relapsesoccurredinnobleareas,whereperipheral
marginwas3mm.Incompletelyexcisedbasalcellcarcinomaoccurredin21patients(1,87%)andweretreatedwithanadditional
excision.Discussion.Althoughguidelinesindicate3mmperipheralmarginofexcisioninBCC2cm,inourexperience,amargin
oflessthan5mmresultsinahighriskofincompleteexcisions.
1.Introduction
cryosurgery, curettage, RT, photodynamic therapy do not
allowhistologicalcon?rmationoftumourclearance.Di?er-
entlysurgicalexcisionwitheitherintraoperativeorpostoper-
ativehistologicalassessmentofthesurgicalmarginsiswidely
used to treat BCC and is generally considered to have the
lowestoverallfailurerateinBCCtreatment[1
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