Basal Cell Carcinoma 10 Years of Experience英文文献资料.docVIP

Basal Cell Carcinoma 10 Years of Experience英文文献资料.doc

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Basal Cell Carcinoma 10 Years of Experience英文文献资料

HindawiPublishingCorporation JournalofSkinCancer Volume2011,ArticleID476362,5pages doi:10.1155/2011/476362 ClinicalStudy BasalCellCarcinoma:10YearsofExperience EmanueleCigna,MauroTarallo,MicheleMaruccia,ValentinaSorvillo, AlessiaPollastrini,andNicolo`Scuderi DepartmentofPlasticandReconstructiveSurgery,PoliclinicoUmbertoI,00161Rome,Italy CorrespondenceshouldbeaddressedtoEmanueleCigna,emanuelecigna@ Received27August2010;Revised15October2010;Accepted1November2010 AcademicEditor:DanielaMassi Copyright?2011EmanueleCignaetal. This is an open access article distributed under the Creative Commons Attribution License,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperly cited. Introduction.Basalcellcarcinoma(BCC)isalocallyinvasivemalignantepidermaltumour.Incidenceisincreasingby10%peryear; incidenceofmetastasesisminimal,butrelapsesarefrequent(40%–50%).ThecompleteexcisionoftheBCCallowsreductionof relapse.MaterialsandMethods.Thestudycohortconsistsof1123patientsunderwentsurgeryforbasalcellcarcinomabetween1999 and2009.Patientandtumorcharacteristicsrecordedare:age;gender;localization(headandneck,trunk,andupperandlower extremities),tumorsize,excisionalmarginsadopted,andrelapses.Results.Thestudyconsideredagroupof1123patientsa?ected bybasalcellcarcinoma.Relapsesoccurredin30cases(2,67%),27outof30relapsesoccurredinnobleareas,whereperipheral marginwas3mm.Incompletelyexcisedbasalcellcarcinomaoccurredin21patients(1,87%)andweretreatedwithanadditional excision.Discussion.Althoughguidelinesindicate3mmperipheralmarginofexcisioninBCC2cm,inourexperience,amargin oflessthan5mmresultsinahighriskofincompleteexcisions. 1.Introduction cryosurgery, curettage, RT, photodynamic therapy do not allowhistologicalcon?rmationoftumourclearance.Di?er- entlysurgicalexcisionwitheitherintraoperativeorpostoper- ativehistologicalassessmentofthesurgicalmarginsiswidely used to treat BCC and is generally considered to have the lowestoverallfailurerateinBCCtreatment[1

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