Cancer and the Web英文文献资料.docVIP

ComparativeandFunctionalGenomics CompFunctGenom2001;2 :35–43. WebsiteReview Cancerandtheweb MarkRobertAlbertella* KuDOSPharmaceuticalsLtd,327CambridgeSciencePark,MiltonRoad,CambridgeCB40WG,UK Abstract *Correspondenceto: M.R.Albertella,KuDOS The applications of functional genomics, proteomics and informatics to cancer research PharmaceuticalsLtd, 327CambridgeSciencePark, MiltonRoad,Cambridge CB40WG,UK. E-mail: malbertella@kudospharma.co.uk have yielded a tremendous amount of information, which is growing all the time. Much of this information is available publicly on the Internet and ranges from general information about different cancers from a patient or clinical viewpoint, through to databases suitable for cancer researchers of all backgrounds, to very speci?c sites dedicated to individual genes or molecules. A simple search for ‘cancer’ from a typical Web browser search engine yields more than half a million hits; an even more speci?c search for ‘leukaemia’ (40000 hits) or ‘p53’ (5700 hits) yields far too manyhitstoallowonetoidentifyparticularsitesofinterest.Thisreviewaimstoprovidea brief guide to some of the resources and databases that can be used as springboards to home in rapidly on information relevant to many ?elds of cancer research. As such, thisarticlewillnotfocusonasinglewebsitebuthopestoillustratesomeofthewaysthat postgenomic biology is revolutionizing cancer research. It will cover genomics and proteomics approaches that have been applied to studying global expression patterns in cancers, in addition to providing links ranging from general information aboutcancertospeci?ccancergenemutationdatabases.Copyright#2001JohnWiley Sons,Ltd. Astartingpointfornewcancer researchers speci?c sets of information about each cancer, generally from a more clinical viewpoint. The whole site can also be searched for individual or There is a good general introduction to cancer combined terms, or just the Cancer News section, biology at the National Centre