Castleman’s Disease of the Pleura Case Presentation and Review of Literature英文文献资料.docVIP

International Journal of Clinical Medicine, 2012, 3, 311-317 311 /10.4236/ijcm.2012.34062 Published Online July 2012 (http://www.SciRP.org/journal/ijcm) Castleman’s Disease of the Pleura: Case Presentation and Review of Literature Pablo Loarte , Nayle Araguez , Rose Marie Flores , Li-The Wu , Ronny Cohen 1 1 1,2 3 1,2* 1 2 3 Woodhull Medical Center, Brooklyn, USA; NYU School of Medicine, New York, USA; North Shore University Hospital, Forest Hills, USA. * Email: ronny.cohen@ Received March 11 , 2012; revised April 25 , 2012; accepted May 16 , 2012 th th th ABSTRACT Purpose: Castleman’s Disease is a very rare medical disease and the presence of this condition in the pleura is even rarer and there are only few reported cases. The presence of symptoms is also unusual and has been mostly described in multicentric cases of castleman’s disease instead of solitary lesions (unicentric castleman). We report a case of unicen- tric pleural castlema’s disease with presence of constitutional symptoms. Methods: A 36-year-old male without any significant past medical history who presented to the emergency due to an incidental large pleural effusion seen in chest radiograph, but referring chronic constitutional symptoms consistent of significant weight loss and chronic cough. Re- sults: Chest computed tomography revealed a mass and several attemps with minimally invase approach failed to iden- tify the lesion. The mass was excised through VATS but due to its significant vascularity, it had to be converted to open thoracotomy. Conclusion: The treatment of unicent