鲁登巴赫综合征7例临床分析-内科急危重症杂志.doc

鲁登巴赫综合征7例临床分析 华中科技大学同济医学院附属同济医院 杨向俐 肖淼淼 吕家高 林立 李晟(，武汉 430000 摘要 目的：观察鲁综(Lutembachers syndrome)的发况、疗及预 方法：回顾性2012年至2015年共7例接受治疗的鲁综临资疗预况2例，女5例；年龄39～67）岁。经疗4例保守治疗结随访6访1随访时间3个2年，患者均为存状态术脏无残余动脉压35±4.6）mmHg，射血分数（68±7闷状显缓NYHA分级为级手术患闷状较缓NYHA分级级结论鲁综征应及时手术治疗对无显变形无严钙关闭间损位封闭术条疗选择Lutembachers syndrome YANG Xiang-li XIAO Miao-miao L(U) Jia-gao LIN Li LI Sheng(. Tongji Hospital of Tongji Medical College of Huazhong University of Science ＆ Technology,Wuhan 430000,China Abstract Objective: To observe the morbidity, pathogeny, treatment and outcome of Lutembachers syndrome. Methods: Clinical data of 7 cases of Lutembachers syndrome who underwent treatment from 2012 to 2015 were analyzed. There were 2 males and 5 females between the ages of 39 and 67. Percutaneous treatment was performed in 2 cases. Surgical treatment was performed in 1 case. And medical therapy was performed in 4 cases. Results: 6 patients were followed up for between 3 months and 2 years, among them, percutaneous treatment was performed in 2 cases, surgical treatment was performed in 1 case, and medical therapy was performed in 3 cases, and 1 patient were lost to followed up. All the patients were alive. For patients underwent percutaneous treatment and surgical treatment, as measured by echocardiography post-operation, there was no residual shunt. The pulmonary artery pressure was （35±4.6）mmHg. The ejection fraction was (68±7) %. The symptoms of chest distress and shortness of breath greatly improved. All patients were class Ⅱ(New York Heart Association). For patients underwent medical therapy, the symptoms of chest distress and shortness of breath were relieved slightly.The patients were class (Ⅲ-Ⅳ)(New York Heart Association). Conclusion: Lutembachers syndrome needs timely percutaneous treatment or surgical intervention. For patients without Serious deformation, calcification and regurgitation of mitral valve and with the position and size of atrial septal defect reachin