An Integration of Genome-Wide Association Study and Gene Expression Profiling to Prioritize the Discovery of Novel Susceptibility Loci for Osteoporosis-Related Traits 英文参考文献.docVIP

AnIntegrationofGenome-WideAssociationStudyand GeneExpressionProfilingtoPrioritizetheDiscoveryof NovelSusceptibilityLociforOsteoporosis-RelatedTraits Yi-HsiangHsu1,2,3.,M.CarolaZillikens4,5.,ScottG.Wilson6,7,8.,CharlesR.Farber9. ,Serkalem Demissie3,10,NicoleSoranzo6,11,EstelleN.Bianchi12,ElinGrundberg11,13,14,LimingLiang15,J.Brent Richards6,13,16,KarolEstrada4,5,YanhuaZhou3,10,AtilavanNas17,MiriamF.Moffatt18,GuangjuZhai6, AlbertHofman5,19,JoyceB.vanMeurs4,5,HuibertA.P.Pols4,19,RogerI.Price7,OlleNilsson20 ,Tomi Pastinen13,14,L.AdrienneCupples3,10,AldonsJ.Lusis21,EricE.Schadt22,SergeFerrari12,Andre′ G. Uitterlinden4,5,19,FernandoRivadeneira4,5,19.,TimothyD.Spector6.,DavidKarasik1,3.*, DouglasP. Kiel1,3. * 1HebrewSeniorLifeInstituteforAgingResearchandHarvardMedicalSchool,Boston,Massachusetts,UnitedStatesofAmerica,2MolecularandIntegrativePhysiological SciencesProgram,HarvardSchoolofPublicHealth,Boston, Massachusetts,UnitedStatesofAmerica, 3FraminghamHeartStudy,Framingham,Massachusetts,United States of America, 4Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands, 5Netherlands Genomics Initiative, The Hague, The Netherlands,6DepartmentofTwinResearchandGeneticEpidemiology,King’sCollegeLondon,London,UnitedKingdom,7DepartmentsofEndocrinology,Diabetes,and Medical Technology and Physics, Sir Charles Gairdner Hospital, Perth, Australia, 8School of Medicine and Pharmacology, University of Western Australia, Crawley, Australia,9DepartmentofMedicine,DivisionofCardiovascularMedicineandCenterforPublicHealthGenomics,UniversityofVirginia,Charlottesville,Virginia,United StatesofAmerica,10DepartmentofBiostatistics,SchoolofPublicHealth,BostonUniversity,Boston,Massachusetts,UnitedStatesofAmerica,11WellcomeTrustSanger Institute, Hinxton, Cambridge, United Kingdom, 12Service of Bone Diseases, Department of Rehabilitation and Geriatrics, University Geneva Hospital, Geneva, Switzerland, 13Department ofHuman Genetics, McGill University,Montrea