- 1、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。。
- 2、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
- 4、该文档为VIP文档,如果想要下载,成为VIP会员后,下载免费。
- 5、成为VIP后,下载本文档将扣除1次下载权益。下载后,不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后,您将拥有八大权益,权益包括:VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传,每下载1次, 网站将根据用户上传文档的质量评分、类型等,对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
Bone T-Scores and Functional Status A Cross-Sectional Study on German Elderly 英文参考文献
BoneT-ScoresandFunctionalStatus:ACross-Sectional
StudyonGermanElderly
ShomaBerkemeyer1*,JochenSchumacher2,UlrichThiem1,LudgerPientka1
1DepartmentofGeriatrics,UniversityofBochum,MarienhospitalHerne,Herne,Germany,2DepartmentofInternalMedicine,AlfriedKruppKrankenhausSteele,University
ofDuisburg-Essen,Essen,Germany
Abstract
Background:WeexploretheassociationbetweenboneT-scores,usedinosteoporosisdiagnosis,andfunctionalstatussince
wehypothesizedthatbonehealthcanimpactelderlyfunctionalstatusandindirectlyindependence.
Methods:Inacross-sectionalstudy(2005–2006)oncommunitydwellingelderly(.=75years)fromHerne,Germanywe
measured bone T-scores with Dual-energy X-ray Absorptiometry, and functional status indexed by five geriatric tests:
activitiesofdailyliving,instrumentalactivitiesofdailyliving,testofdementia,geriatricdepressionscoreandthetimed-up-
and-go test, and two pooled indexes: raw and standardized. Generalized linear regression was used to determine the
relationshipbetweenT-scoresandfunctionalstatus.
Results:From3243addresses,only632(19%)completedaclinicalvisit,ofwhichonly440(male:female,243:197)couldbe
includedinanalysis.T-scores(20.99,95%confidenceinterval[CI],21.1–0.9)predictedactivitiesofdailyliving(95.3CI,94.5–
96.2), instrumental activities of daily living (7.3 CI, 94.5–96.2), and timed-up-and-go test (10.7 CI, 10.0–11.3) (P, =0.05).
PooleddatashowedthataunitimprovementinT-scoreimprovedstandardizedpooledfunctionalstatus(15CI,14.7–15.3)
by 0.41 and the raw (99.4 CI, 97.8–101.0) by 2.27 units. These results were limited due to pooling of different scoring
directions,selectionbias,andaneedtofollow-upwithevidencetesting.
Conclusions: T-scores associated with lower functional status in community-dwelling elderly. Regular screening of
osteoporosisasapreventivestrategymighthelpmaintainlifequalitywithaging.
Citation: Berkemeyer S, Schumacher J, Thiem U, Pientka L (2009) Bone T-Scores and Functional Status: A Cross-Sectional Study on German Elderly. PLoS
ONE4(12):e8216.doi
您可能关注的文档
- Blindness in Childhood in Developing Countries Time for a Reassessment 英文参考文献.doc
- Black Petrels (Procellaria parkinsoni) Patrol the Ocean Shelf-Break GPS Tracking of a Vulnerable Procellariiform Seabird 英文参考文献.doc
- Blindness Survey Methods Response from Sudan Study Authors 英文参考文献.doc
- Blinding Trachoma A Disease of Poverty 英文参考文献.doc
- Blockade of Immunosuppressive Cytokines Restores NK Cell Antiviral Function in Chronic Hepatitis B Virus Infection 英文参考文献.doc
- Blockade of Pachytene piRNA Biogenesis Reveals a Novel Requirement for Maintaining Post-Meiotic Germline Genome Integrity 英文参考文献.doc
- Blockade of the BAK Hydrophobic Groove by Inhibitory Phosphorylation Regulates Commitment to Apoptosis 英文参考文献.doc
- Blockade of VEGFR1 and 2 Suppresses Pathological Angiogenesis and Vascular Leakage in the Eye 英文参考文献.doc
- Blebbistain, a Myosin II Inhibitor, as a Novel Strategy to Regulate Detrusor Contractility in a Rat Model of Partial Bladder Outlet Obstruction 英文参考文献.doc
- Blockade of Neuronal α7-nAChR by α-Conotoxin ImI Explained by Computational Scanning and Energy Calculations 英文参考文献.doc
- Bone Quality An Empty Term 英文参考文献.doc
- Bone Surface Mapping Method 英文参考文献.doc
- Bone Mineral Density in HIV-Negative Men Participating in a Tenofovir Pre-Exposure Prophylaxis Randomized Clinical Trial in San Francisco 英文参考文献.doc
- Bonsai Trees in Your Head How the Pavlovian System Sculpts Goal-Directed Choices by Pruning Decision Trees 英文参考文献.doc
- Boosting of Synaptic Potentials and Spine Ca Transients by the Peptide Toxin SNX-482 Requires Alpha-1E-Encoded Voltage-Gated Ca Channels 英文参考文献.doc
- Bone Turnover and Metabolism in Patients with Early Multiple Sclerosis and Prevalent Bone Mass Deficit A Population-Based Case-Control Study 英文参考文献.doc
- Bone Tissue Response to Porous and Functionalized Titanium and Silica Based Coatings 英文参考文献.doc
- Bordetella pertussis Infection or Vaccination Substantially Protects Mice against B. bronchiseptica Infection 英文参考文献.doc
- Botany, Genetics and Ethnobotany A Crossed Investigation on the Elusive Tapir's Diet in French Guiana 英文参考文献.doc
- Borrelia recurrentis Employs a Novel Multifunctional Surface Protein with Anti-Complement, Anti-Opsonic and Invasive Potential to Escape Innate Immunity 英文参考文献.doc
文档评论(0)