Fish Tank Granuloma Caused by Mycobacterium marinum 英文参考文献.docVIP

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Fish Tank Granuloma Caused by Mycobacterium marinum 英文参考文献.doc

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Fish Tank Granuloma Caused by Mycobacterium marinum 英文参考文献

FishTankGranulomaCausedbyMycobacterium marinum Ting-ShuWu1,2,Cheng-HsunChiu3,Chih-HsunYang4,Hsieh-ShongLeu1,Ching-TaiHuang1 ,Yi- ChiehChen5,Tsu-LanWu6,7,Pi-YuehChang6,7,8,Lin-HuiSu6,7,An-JingKuo6,7,Ju-HsinChia6,7,8 ,Chia- ChenLu9,Hsin-ChihLai7,8,10* 1Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan, 2Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan, 3Division of Infectious Diseases, Department of Pediatrics, Chang Gung Children’sHospital,ChangGungMemorialHospital,ChangGungUniversityCollegeofMedicine,Taoyuan,Taiwan,4DepartmentofDermatology,ChangGungMemorial Hospital,ChangGung,Taoyuan,Taiwan,5DepartmentofPlasticandReconstructiveSurgery,ChangGungMemorialHospital,ChangGungUniversityCollegeofMedicine, Taoyuan,Taiwan,6DepartmentofLaboratoryMedicine,ChangGungMemorialHospital,ChangGungUniversityCollegeofMedicine,Taoyuan,Taiwan,7Departmentof MedicalBiotechnologyandLaboratorySciences,ChangGungUniversity,Taoyuan,Taiwan,8GraduateInstituteofMedicalBiotechnologyandLaboratorySciences,Chang Gung University, Taoyuan, Taiwan, 9Department of Respiratory Therapy, Fu-Jen Catholic University, New Taipei, Taiwan, 10Research Center for Pathogenic Bacteria, ChangGungUniversity,Taoyuan,Taiwan Abstract Introduction:Mycobacteriummarinumcausesskinandsofttissue,boneandjoint,andraredisseminatedinfections.Inthis study, we aimed toinvestigate therelationship between treatment outcome and antimicrobial susceptibility patterns. A totalof27patientswithM.marinuminfectionswereenrolled. Methods:Dataonclinicalcharacteristicsandtherapeuticmethodswerecollectedandanalyzed.Wealsodeterminedthe minimuminhibitoryconcentrationsof7antibioticsagainst30isolatesfromthesepatients. Results:Twenty-sevenpatientsreceivedantimycobacterialagentswithorwithoutsurgicaldebridement.Eighteenpatients werecured,8 failedtorespond totreatment,andone waslost tofollow-up. Theduration ofclar