Pongaflavanol a Prenylated Flavonoid from Pongamia pinnata with a Modified Ring A 英文参考文献.docVIP
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Pongaflavanol a Prenylated Flavonoid from Pongamia pinnata with a Modified Ring A 英文参考文献
Molecules 2006, 11, 786-791
molecules
ISSN 1420-3049
Full Paper
Pongaflavanol: a Prenylated Flavonoid from Pongamia pinnata
with a Modified Ring A
Hao Yin 1, Si Zhang 1,2,*, Jun Wu 1, Haihan Nan 1, Lijuan Long 1, Jin Yang 1 and Qingxin Li 1
1 Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology,
Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou, 510301, P.R. China, Tel. /
Fax: +86 20 E-mail: yin_hao_gz@
2 Hainan Key Lab of Tropical Marine Biotechnology, Chinese Academy of Science, Sanya, 572000,
P.R. China
* Author to whom correspondence should be addressed; E-mail: zhsimd@
Received: 13 September 2006; in revised form 16 October 2006 / Accepted: 16 October 2006 /
Published: 20 October 2006
Abstract: A new prenylated flavon-4-ol with a modified ring A, which we have named
pongaflavanol (1), was isolated from the stem bark of Pongamia pinnata along with the
known compound tunicatachalcone (2). The structure of compound 1 was elucidated on
the basis of spectroscopic data.
Keywords: Flavonoids, flavan-4-ol, modified ring A, Pongamia pinnata
Introduction
Pongamia pinnata (Linn) Pierre (Leguminosae, Papilionacea; synonym: Pongamia glabra Vent; is
a medium sized glabrous tree (common names: pongam, Indian beech) that grows in the litoral regions
of South Eastern Asia and Australia. All parts of this plant have been used as crude drugs for the
treatment of tumors, piles, skin diseases, wounds and ulcers [1]. Its extracts possess significant
antidiarrhoeal, antifungal, antiplasmodial, antiulcerogenic, antiinflammatory and analgesic activities
[2-6]. Previous phytochemical investigation of this plant indicated the presence of abundant prenylated
flavonoids such as furanoflavones, furanoflavonols, chromenoflavones, furanochalcones, and
pyranochalcones [1, 7-9]. During our continuing study of this plant, two prenylated flavonoid
Mole
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