Primary carcinoid tumor arising within mature teratoma of the kidney report of a rare entity and review of the literature 英文参考文献.docVIP

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Primary carcinoid tumor arising within mature teratoma of the kidney report of a rare entity and review of the literature 英文参考文献.doc

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Primary carcinoid tumor arising within mature teratoma of the kidney report of a rare entity and review of the literature 英文参考文献

Diagnostic Pathology BioMedCentral Review Open Access Primary carcinoid tumor arising within mature teratoma of the kidney: report of a rare entity and review of the literature Henry B Armah* and Anil V Parwani Address: Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA Email: Henry B Armah* - armahh2@; Anil V Parwani - parwaniav@ * Corresponding author Published: 17 May 2007 Received: 27 April 2007 Accepted: 17 May 2007 Diagnostic Pathology 2007, 2:15 doi:10.1186/1746-1596-2-15 This article is available from: /content/2/1/15 ? 2007 Armah and Parwani; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Primary carcinoid tumor arising within mature teratoma of the kidney is extremely rare, and their clinicopathologic features are not well described. Our objective was to further define the clinical features and pathologic spectra of primary carcinoid tumor arising within mature teratoma of the kidney. Methods: Six previously reported case reports were identified using MEDLINE and a subsequent bibliographic search of all pertinent reports and reviews was performed. We also searched the electronic medical archival records of our institution and identified one additional unreported case. Data were extracted on the demographics, predisposing factors, clinical presentation, radiographic features, gross pathology, microscopic pathology, immunophenotype, therapy, and outcome of each of these seven cases. Results: Primary carcinoid tumor arising within mature teratoma of the kidney was found at a mean age of 41.4 years. Of the 7 cases, 3 were female and 4 were male. Two of the 7 cases (28.6%) were associated with horseshoe kidney. It typically