Prevalence of radiographic detectable intervertebral disc calcifications in Dachshunds surgically treated for disc extrusion 英文参考文献.docVIP

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Prevalence of radiographic detectable intervertebral disc calcifications in Dachshunds surgically treated for disc extrusion 英文参考文献.doc

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Prevalence of radiographic detectable intervertebral disc calcifications in Dachshunds surgically treated for disc extrusion 英文参考文献

Rohdin et al. Acta Veterinaria Scandinavica 2010, 52:24 /content/52/1/24 RESEARCH Open Access Prevalence of radiographic detectable Research intervertebral disc calcifications in Dachshunds surgically treated for disc extrusion Cecilia Rohdin*1, Janis Jeserevic2, Ranno Viitmaa3 and Sigitas Cizinauskas2 Abstract Background: An association between the occurrence of calcified discs, visible on radiographic examination (CDVR), and disc extrusions has been suggested in published literature over the past 10-20 years, mainly from Nordic countries. It has also been postulated that dogs without CDVR would not develop disc extrusions. Furthermore, inheritance of CDVR has been calculated and it has been postulated that, by selecting dogs for breeding with few, or no CDVR, the prevalence of disc extrusions in the Dachshund population may be reduced. Methods: The prevalence of radiographic detectable intervertebral disc calcifications was calculated from one hundred surgeries for disc extrusion, performed in 95 Dachshunds, in order to determine if the disc causing clinically significant IVDD, had radiographic signs of calcification at the time of confirmed disc extrusion. Inclusion criteria, for each dog, included a complete physical, orthopedic and neurologic examination, radiographs of the entire vertebral column, a myelogram or magnetic resonance imaging examination indicating extradural spinal cord compression, and finally a surgical procedure confirming the diagnosis of a disc extrusion. In addition to descriptive statistics, age correlation with number of calcifications visible at radiographic examination and with CDVR at the surgery site was examined. Results: We found that disc extrusions occur as frequently in discs that are found to have radiographic evidence of calcification as those discs that do not have signs of radiographic calcification, and that IVDD (intervertebral disc disease) requiring surgery does occur in the absence of any calcified discs