Prevalence, Causes and Socio-Economic Determinants of Vision Loss in Cape Town, South Africa 英文参考文献.docVIP
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Prevalence, Causes and Socio-Economic Determinants of Vision Loss in Cape Town, South Africa 英文参考文献
Prevalence,CausesandSocio-EconomicDeterminantsof
VisionLossinCapeTown,SouthAfrica
NickyCockburn1*,DavidSteven2,KarinLecuona1,FrancoisJoubert1,GraemeRogers1,ColinCook1,
SarahPolack3
1DepartmentofOphthalmology,GrooteSchuurHospital,CapeTown,SouthAfrica,2EersteRiverHospital,CapeTown,SouthAfrica,3LondonSchoolofHygieneand
TropicalMedicine,London,UnitedKingdom
Abstract
Purpose: To estimate the prevalence and causesof blindness and visual impairment in Cape Town, South Africa and to
exploresocio-economicanddemographicpredictorsofvisionlossinthissetting.
Methods:Acrosssectionalpopulation-basedsurveywasconductedinCapeTown.Eighty-twoclusterswereselectedusing
probability proportionate tosize sampling. Within eachcluster 35 or40 people aged 50 years and above were selected
usingcompactsegmentsampling.Visualacuityofparticipantswasassessedandeyeswithavisualacuitylessthan6/18
were examined by an ophthalmologist to determine the cause of vision loss. Demographic data (age, gender and
education)werecollectedandasocio-economicstatus(SES)indexwascreatedusingprincipalcomponentsanalysis.
Results:Outof3100eligiblepeople,2750(89%)wereexamined.Thesampleprevalenceofbilateralblindness(presenting
visualacuity,3/60)was1.4%(95%CI0.9–1.8).Posteriorsegmentdiseasesaccountedfor65%ofblindnessandcataractwas
responsiblefor27%.Theprevalenceofvisionlosswashighestamongpeopleover80years(oddsratio(OR)6.995%CI4.6–
10.6),thoseinthepoorestSESgroup(OR3.995%CI2.2–6.7)andpeoplewithnoformaleducation(OR5.495%CI1.7–16.6).
Cataract surgical coverage was 68% in the poorest SES tertile (68%) compared to 93% in the medium and 100% in the
highesttertile.
Conclusions: The prevalence of blindness among people $50 years in Cape Town was lower than expected and the
contributionofposteriorsegmentdiseaseshigherthanpreviouslyreportedinSouthAfricaandSubSaharanAfrica.There
wereclearsocio-economicdisparitiesinprevalenceofvisionlossandcataractsurgicalcoverageinthissettingwhichneed
tobeaddressedinblindnesspreventionprograms.
Citatio
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