Promoting Physical Activity in Patients with Colon Adenomas A Randomized Pilot Intervention Trial 英文参考文献.docVIP

Promoting Physical Activity in Patients with Colon Adenomas A Randomized Pilot Intervention Trial 英文参考文献.doc

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Promoting Physical Activity in Patients with Colon Adenomas A Randomized Pilot Intervention Trial 英文参考文献

PromotingPhysicalActivityinPatientswithColon Adenomas:ARandomizedPilotInterventionTrial KathleenY.Wolin*,CaseyFagin,AimeeS.James,DaynaS.Early WashingtonUniversitySchoolofMedicineandSitemanCancerCenter,StLouis,Missouri,UnitedStatesofAmerica Abstract Background: Physical activity decreases risk of colon polyps and colon cancer and might reduce risk of colon cancer recurrence.Focusingonrecentcallsfortranslationofepidemiologicevidenceintoclinicalcare,ourpilotstudydeliveredan evidence-based physical activity intervention in adults with polyps, who are thus at elevated risk of developing colon cancer.Theobjectivewastoevaluatechangeinphysicalactivity,measuredbystepsperdayandminutesofmoderate/ vigorousphysicalactivity. Methods: Sixteen adults with adenomas detected and removed at screening colonoscopy were recruited to a 12-week physicalactivityintervention.Participantswererandomizedtoreceiveastandard(30minutes/day)orhigh(60minutes/day) walking program. Physical activity was measured via blinded pedometer and accelerometer at baseline and follow-up. Intervention messages focused on self-monitoring using pedometers and overcoming barriers to engaging in physical activity. Results: Participants in both arms significantly increased objectively measured minutes of moderate/vigorous physical activity over the course of the intervention. Both arms exceeded the intervention goal, but there was not a significant difference between arms at follow-up. Results were similar for pedometer measured physical activity, with a significant overallincreaseinsteps/dayfrombaselinetofollow-up,butnobetweenarmdifferenceinchange. Conclusion:Simpleinterventionsofminimalcontacttimefocusingonwalkingcansignificantlyincreasephysicalactivityin individualsatincreasedriskofdevelopingcoloncancer. TrialRegistration:ClinicalTNCCitation:WolinKY,FaginC,JamesAS,EarlyDS(2012)PromotingPhysicalActivityinPatientswithColonAdenomas:ARandomizedPilotInterventionTrial.PLoS ONE7(7):e39719.doi:10.1371/journal.p

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