Proteinuria Is Associated with Quality of Life and Depression in Adults with Primary Glomerulopathy and Preserved Renal Function 英文参考文献.docVIP

下载本文档

4
0
约3.19万字
约 6页
2017-05-13 发布于上海
举报
版权申诉

Proteinuria Is Associated with Quality of Life and Depression in Adults with Primary Glomerulopathy and Preserved Renal Function 英文参考文献.doc

1、本文档共6页，可阅读全部内容。
2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
5、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
6、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
7、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
8、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

Proteinuria Is Associated with Quality of Life and Depression in Adults with Primary Glomerulopathy and Preserved Renal Function 英文参考文献

ProteinuriaIsAssociatedwithQualityofLifeand DepressioninAdultswithPrimaryGlomerulopathyand PreservedRenalFunction AlexandreBragaLibo′rio1,3*,Joa?oPauloLimaSantos2,Nata′liaFeitosaArraesMinete2,Cec?′liade AlencarDio′genes2,ArianePontesSoares2,AnaiaraLucenaQueiroz3,DulceMariaSilvaBarreto3 1Post-GraduatePrograminPublicHealth,UNIFOR,Fortaleza,Ceara′, Brazil,2MedicalCourse,UniversityofFortaleza,UNIFOR,Fortaleza,Ceara′, Brazil,3HospitalGeralde Fortaleza,Fortaleza,Ceara′, Brazil Abstract Background:ThereisnoinformationaboutHRQoL,depressionandassociatedfactorsinadultwithnephroticsyndrome- associatedglomerulopathy. Methodology/Principal Findings: Patients with primary glomerulopathy where compared with age and sex-matched hemodialysis patients and healthy subjects. Laboratory data, medical history, comorbid conditions were collected to evaluate factors associated with HRQoL (SF-36) and Depression (Hamilton Depression Rating Scale - HAMD). Glomerulopathy patients had low HRQoL in all eight SF-36 domains and two composite scores (physical and mental) in comparisonwithhealthysubjects.HAMDscorealsowaselevatedandtherewashighdepressionprevalence.Overall,these data were comparable between glomerulopathy and hemodialysis patients. Using multiple regression analysis, factors associated with low HRQoL physical composite score were: last 24h-urine protein excretion (20.183, 95%CI 20.223 to 20.710 for each gram of proteinuria, p=0.01) and cyclosporine use (215.315, 95%CI 225.913 to 22.717, p=0.03). Low HRQoLmentalcompositescorewasassociatedwithlast24h-urineproteinexcretion(20.157,95%CI20.278to20.310for eachgramofproteinuria,p=0.03)andHMADscorewasindependentlyassociatedwithage(0.155,95%CI0.318to0.988for eachyear,p=0.04),femalesex(4.788,95%CI1.005to8.620,0=0.03),diseaseduration(0.074,95%CI0.021to0.128foreach month,p=0.01)andlast24h-urineproteinexcretion(0.050,95%CI0.018to0.085foreachgramofproteinuria,p=0.02). Conclusions/Significance:Nephrotic-syndromeassociatedglomerulopathyp