Pulse pressure variation, stroke volume variation and dynamic arterial elastance 英文参考文献.docVIP

Giraud et al. Critical Care 2011, 15:414 /content/15/2/414 LETTER Pulse pressure variation, stroke volume variation and dynamic arterial elastance Raphael Giraud, Nils Siegenthaler and Karim Bendjelid* See related research by Monge Garcia et al., /content/15/1/R15 We read with interest the recent article by Monge Garcia and colleagues [1]. We have two comments regarding this interesting physiological study. conventionally [4], the ratio PPV/SVV becomes a FT mirror of a dynamic Ea, as the conventional PPV selected integrates Khi (Figure 1). However, when the present First, although we support their observation [2], their innovative method is used, PPV and SVV should be explanations may lead to some confusion. Indeed, the sampled during the same period of time. Edwards Vigileo TM system-FloTrac TM sensor calculates In conclusion, we believe that dynamic Ea predicting arterial pressure response to volume loading in preload- dependent patients is an interesting physiological con- cept. However, this demonstration cannot be achieved without taking into consideration the impact of PPV/ SVV sampling. stroke volume (SV) using the equation: SV = Khi × σAP where σAP is the standard deviation of the arterial pressure (AP) curve and Khi a constant quantifying arterial elastance and vascular resistance [3]. As stroke volume variation (SVV): Abbreviations AP, arterial pressure; Ea, arterial elastance; PP, pulse pressure; PPV, pulse pressure variation; SV, stroke volume; SVV, stroke volume variation. Competing interests The authors declare that they have no competing interests. SVV (in %) = (SVmax – SVmin)/SV mean SVV (%) = (Khi × σAPmax – Khi × σAPmin)/Khi × σAPmean SVV (%) = Khi × (σAPmax – σAPmin)/Khi × σAPmean Published: 23 March 2011 References 1. Monge Garcia MI, Gil Cano A, Gracia Ro mero M: Dynamic arterial elastance to predict arterial pressure respo