Quantitative analysis of DNA levels in maternal plasma in normal and Down syndrome pregnancies 英文参考文献.docVIP

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Quantitative analysis of DNA levels in maternal plasma in normal and Down syndrome pregnancies 英文参考文献.doc

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Quantitative analysis of DNA levels in maternal plasma in normal and Down syndrome pregnancies 英文参考文献

BMC Pregnancy and Childbirth BioMedCentral BMC2002Pregnancy, and Childbirth 2 Research article x Quantitative analysis of DNA levels in maternal plasma in normal and Down syndrome pregnancies Ilona Hromadnikova*1, Bela Houbova1, Dana Hridelova1, Sona Voslarova1, Pavel Calda2, Katerina Nekolarova2, Josef Kofer3, David Stejskal4, Jindrich Doucha5, Ondrej Cinek1 and Jan Vavrirec1 Address: 12nd Department of Paediatrics, 2nd Medical Faculty, Charles University, University Hospital Motol, Czech Republic, 2Department of Obstetrics and Gynaecology, 1st Medical Faculty, Charles University, Prague, Czech Republic, 3Department of Medical Genetics, Masaryk Hospital, ústi nad Labem, Czech Republic, 4Department of Medical Genetics, GENNET, Prague, Czech Republic and 5Department of Obstetrics and Gynaecology, 2nd Medical Faculty, Charles University, University Hospital Motol, Prague, Czech Republic E-mail: Ilona Hromadnikova* - ilona.hromadnikova@lfmotol.cuni.cz; Bela Houbova - ilona.hromadnikova@lfmotol.cuni.cz; Dana Hridelova - ilona.hromadnikova@lfmotol.cuni.cz; Sona Voslarova - ilona.hromadnikova@lfmotol.cuni.cz; Pavel Calda - calda@obgyn.anet.cz; Katerina Nekolarova - calda@obgyn.anet.cz; Josef Kofer - josef.kofer@mnul.cz; David Stejskal - david.stejskal@gennet.cz; Jindrich Doucha - ilona.hromadnikova@lfmotol.cuni.cz; Ondrej Cinek - ondrej.cinek@lfmotol.cuni.cz; Jan Vavrirec - jan.vavrinec@lfmotol.cuni.cz *Corresponding author Published: 28 May 2002 Received: 9 January 2002 Accepted: 28 May 2002 BMC Pregnancy and Childbirth 2002, 2:4 This article is available from: /1471-2393/2/4 ? 2002 Hromadnikova et al; licensee BioMed Central Ltd. Verbatim copying and redistribution of this article are permitted in any medium for any purpose, provided this notice is preserved along with the articles original URL. Abstract Background: We investigated fetal and total DNA levels in maternal plasma in patients bearing fetuses affected with Down syndrome