Respiratory function of people with amyotrophic lateral sclerosis and caregiver distress level a correlational study 英文参考文献.docVIP
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Respiratory function of people with amyotrophic lateral sclerosis and caregiver distress level a correlational study 英文参考文献
Respiratoryfunctionofpeoplewithamyotrophic
lateralsclerosisandcaregiverdistresslevel:
acorrelationalstudy
Pagninietal.
Pagninietal.BioPsychoSocialMedicine2012,6:14
/content/6/1/14
Pagninietal.BioPsychoSocialMedicine2012,6:14
/content/6/1/14
RESEARCH
OpenAccess
Respiratoryfunctionofpeoplewithamyotrophic
lateralsclerosisandcaregiverdistresslevel:
acorrelationalstudy
FrancescoPagnini1*,PaoloBanfi2,3,ChristianLunetta2,GabriellaRossi2,GianlucaCastelnuovo1,4,AnnaMarconi2,
FedericaFossati2,MassimoCorbo2andEnricoMolinari1,4
Abstract
Background:AmyotrophicLateralSclerosis(ALS)isarare,fatalneurodegenerativedisorderwithnocurative
treatmentcharacterizedbydegenerationofmotorneuronsinvolvingaprogressiveimpairmentofmotorand
respiratoryfunctions.Mostpatientsdieofventilatorrespiratoryfailure.Caregivershaveagreatinfluenceonthe
patient”squalityoflifeaswellasonthequalityofcare.Homeinfluenceofthecaregiveronpatientcareisnotable.
Todate,nostudyhasinvestigatedhowpsychologicalissuesofcaregiverswouldinfluencerespiratoryvariablesof
ALSpatients.ThestudyaimedatfindingoutifthereisarelationshipbetweentherespiratoryfunctionofALS
patientsandthelevelofdistressoftheircaregivers.
Methods:Across-sectionalstudywasconductedtoinvestigaterespiratoryissues(PCFandFVC)andtheperception
ofsocialsupportofALSpatients.Caregiversfilledquestionnairesabouttraitanxiety,depression,andburdenofcare.
FortyALSpatientsandtheircaregiverswererecruited.
Results:FVCandPCFwerepositivelyrelatedtopatientperceptionofsocialsupportandnegativelyrelatedto
caregiveranxiety,depression,andburden.
Discussion:ThedistressofALScaregiversisrelatedtopatientrespiratoryissues.Thefirstandmoreintuitive
explanationemphasizestheimpactthatthepatient’sclinicalconditionhaswithrespecttothecaregiver.However,
itispossibletohypothesizethatifcaregiversfeelpsychologicallybetter,theirpatient’squalityoflifeimprovesand
thataconditionofgreaterwell-beingandrelaxationcouldalsoincreaseventilatorycapacity.Furthermore,care
managementcouldbecarriedoutmoreeasilybyc
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