Retooling National TB Control Programmes (NTPs) with New Diagnostics The NTP Perspective 英文参考文献.docVIP

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Retooling National TB Control Programmes (NTPs) with New Diagnostics The NTP Perspective 英文参考文献.doc

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Retooling National TB Control Programmes (NTPs) with New Diagnostics The NTP Perspective 英文参考文献

RetoolingNationalTBControlProgrammes(NTPs)with NewDiagnostics:TheNTPPerspective SanneC.vanKampen1,2*,AndrewR.Ramsay1,RichardM.Anthony2,PaulR.Klatser2 1UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR), World Health Organization, Geneva, Switzerland, 2Royal TropicalInstitute(KIT),KITBiomedicalResearch,Amsterdam,TheNetherlands/AthenaInstitute,FreeUniversityofAmsterdam,TheNetherlands Abstract Background:AdelayisevidentbetweenthedevelopmentofnewpoliciesonTBdiagnosticsandtheirimplementationat country level. The Stop TB Partnership would benefit from information from national TB program (NTP) managers on progresstowardsimplementationofnewrecommendationsaswellastheopportunitiesandchallengesencounteredinthe process. MethodsandFindings:TosolicitinformationontheintroductionofnewTBdiagnosticsatcountrylevel,questionnaires weresentouttoNTPmanagersofhigh-burdenTBcountriesandasubsetofmanagerswasinterviewed.Theresultsindicate thatabout50%ofhigh-burdenTBcountriesareusingtheTBdiagnostictoolsnewlyrecommendedbytheWorldHealth Organization (WHO). Most NTP managers reported that new diagnostics would only be implemented when officially endorsedbytheWHO.Allcountrieshaveplanstoadoptnewlyendorseddiagnosticsatreferencelaboratorylevel,while approaches to optimize smear microscopy at lower levels of the health service are given less attention. NTP managers reporteddiversechallengestotheimplementationofnewdiagnostics. Conclusions:Moreinformationontheobstaclesandadvantagesofintroducingnewdiagnostictoolsshouldbeprovidedto NTPmanagerstoensuretherationaladoptionofnewdiagnostics.Asinglerecommendationcoveringtheintroductionofa package of diagnostic tools might be preferable to NTP managers and facilitate implementation in high-burden TB countries. Citation: van Kampen SC, Ramsay AR, Anthony RM, Klatser PR (2010) Retooling National TB Control Programmes (NTPs) with New Diagnostics: The NTP Perspective.PLoSONE5(7):e11649.doi:10.1371/journal.pone.0011649