Schistosomiasis, Soil-Transmitted Helminthiasis, and Sociodemographic Factors Influence Quality of Life of Adults in C？te dIvoire 英文参考文献.docVIP

Schistosomiasis,Soil-TransmittedHelminthiasis,and SociodemographicFactorsInfluenceQualityofLifeof AdultsinCo?ted’Ivoire ThomasFu¨rst1,2,KigbaforiD.Silue′3,4,MamadouOuattara3,DjeN.N’Goran5,LukasG.Adiossan6, YaoN’Guessan4,FabianZouzou4,SiakaKone′4,Elie′zerK.N’Goran3,4,Ju¨rgUtzinger1,2 * 1Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland, 2University of Basel, Basel, Switzerland, 3Unite′ de FormationetdeRechercheBiosciences,Universite′ deCocody,Abidjan,Co?ted’Ivoire,4CentreSuissedeRecherchesScientifiquesenCo?ted’Ivoire,Abidjan,Co?ted’Ivoire, 5ProgrammeNationaldeLuttecontrelaSchistosomiase,lesGe′ohelminthiasesetlaFilarioseLymphatique,Abidjan,Co?ted’Ivoire,6Ho?pitalGe′ne′raldeTaabo,TaaboCite′, Co?ted’Ivoire Abstract Background: Burdenofdiseaseestimatesarewidelyused forprioritysettingin publichealthanddisability-adjustedlife yearsareapowerful‘‘currency’’nowadays.However,disabilityweights,whichcapturethedisabilityincurredbyatypical patient of a certain condition, are fundamental to such burden calculation and their determination remains a widely debatedissue. Methodology: A cross-sectional epidemiological survey was conducted in the recently established Taabo health demographicsurveillancesystem(HDSS)insouth-centralCo?ted’Ivoire,toprovidenew,population-basedevidenceonthe disabilitycausedbyschistosomiasisandsoil-transmittedhelminthiasis.Parasitologicalresultsfromstool,urine,andblood examinationswerejuxtaposedtoqualityoflife(QoL)questionnaireresultsfrom187adults.Amultivariablelinearregression modelwithstepwisebackwardeliminationwasusedtoidentifysignificantassociations,consideringalsosociodemographic characteristicsobtainedfromtheTaaboHDSSdatabase. Principal Findings: Prevalences for hookworm, Plasmodium spp., Trichuris trichiura, Schistosoma haematobium and Schistosomamansoniwere39.0%,18.2%,2.7%,2.1%and2.1%,respectively. S.mansoniandT.trichiura infections ofany intensity reduced the participants’ sel