Searching for an ideal hemodynamic marker to predict short-term outcome in cardiogenic shock 英文参考文献.docVIP

Available online /content/13/6/1013 Commentary Searching for an ideal hemodynamic marker to predict short-term outcome in cardiogenic shock Mehmet Birhan Yilmaz1,2 and Alexandre Mebazaa2 1Department of Cardiology, School of Medicine, Cumhuriyet University, 58140, Sivas, Turkey 2AP-HP, Department of Anesthesia and Critical Care, Hopital Lariboisiere Paris, Universite Paris Diderot, U942 Inserm, Paris, 75010, France Corresponding author: Alexandre Mebazaa, alexandre.mebazaa@lrb.aphp.fr Published: 10 December 2009 Critical Care 2009, 13:1013 (doi:10.1186/cc8176) This article is online at /content/13/6/1013 ? 2009 BioMed Central Ltd See related research by Torgersen et al., /content/13/5/R157 Abstract mortality risk, around 50% in the acute term [2]. Therefore, it is vital to identify signals driving the CS prognosis. For decades, hemodynamic monitoring has been desired for patients with acute pathologies with the aim of guiding therapy and risk-stratification [3]. Many parameters derived from hemodynamics – such as the cardiac output, systemic blood pressure, systemic vascular resistance, stroke volume, and pulmonary capillary wedge pressure – have so far been investigated to designate prognosis with unequivocal results [4,5]. Among these hemodynamic parameters, the cardiac power output and the CPI serve as interesting markers showing cardiovascular coupling at one glance, in contrast to other parameters that provide information about either the cardiac system or the vascular system [5]. Cardiogenic shock is a lethal condition. Physicians are searching for hemodynamic markers which could help risk-stratification of patients in this picture. Torgersen and coworkers present an hourly time integral of the cardiac power index and cardiac index drops to predict outcomes in the setting of cardiogenic shock. Continuous monitoring of hemodynamic markers may have