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Seroprevalence of Chagas Infection in the Donor Population 英文参考文献
SeroprevalenceofChagasInfectionintheDonor
Population
BenA.Zaniello1*,DeborahA.Kessler2,KatherineM.Vine3,KathleenM.Grima4,ScottA.Weisenberg5
1DepartmentofMedicine,UniversityofWashington,Seattle,Washington,UnitedStatesofAmerica,2SpecialDonorandCommunityHealthServices,NewYorkBlood
Center,NewYork,NewYork,UnitedStatesofAmerica,3SpecialPatientServices,NewYorkBloodCenter,NewYork,NewYork,UnitedStatesofAmerica,4AmericanRed
Cross,Philadelphia,Pennsylvania,UnitedStatesofAmerica,5AltaBatesSummitMedicalCenter,Oakland,California,UnitedStatesofAmerica
Abstract
WeretrospectivelycalculatedtheprevalenceandepidemiologiccharacteristicsofChagasinfectionintheNewYorkblood
donorpopulationoverthreeyearsutilizingtheNewYorkBloodCenter’sdatabaseoftheNewYorkmetropolitanareadonor
population.SeventyTrypanosomacruzipositivedonorswereidentifiedfromamong876,614donorsovera3-yearperiod,
givinganadjustedprevalenceof0.0083%,with0.0080%in2007,0.0073%in2008,and0.0097%in2009.Whenfilteredonly
for self-described ‘‘Hispanic/Latino’’ donors, therewere 52 Chagas positive donorsin that 3-year period (among 105,122
self-describedHispanicdonors)withanadjustedprevalenceof0.052%,with0.055%in2007,0.047%in2008,and0.053%in
2009.Inconclusion,wefoundapersistentpopulationofpatientswithChagasinfectionintheNewYorkmetropolitanarea
donorpopulation.TherewasgeographiclocalizationofcaseswhichalignedwithLatinAmericanimmigrationclusters.
Citation:ZanielloBA,KesslerDA,VineKM,GrimaKM,WeisenbergSA(2012)SeroprevalenceofChagasInfectionintheDonorPopulation.PLoSNeglTropDis6(7):
e1771.doi:10.1371/journal.pntd.0001771
Editor:HeltondaCostaSantiago,NationalInstitutesofHealth,UnitedStatesofAmerica
ReceivedMarch7,2012;AcceptedJune23,2012;PublishedJuly31,2012
Copyright: ? 2012 Zaniello et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits
unrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalauthorandsourcearecredited.
Funding:Theauthorshavenosupportor
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