Serum 25-Hydroxyvitamin D Levels Among Boston Trainee Doctors in Winter 英文参考文献.docVIP

Nutrients 2012, 4, 197-207; doi:10.3390/nu4030197 OPEN ACCESS nutrients ISSN 2072-6643 /journal/nutrients Article Serum 25-Hydroxyvitamin D Levels Among Boston Trainee Doctors in Winter Amanda S. Growdon 1,*, Carlos A. Camargo Jr. 2, Sunday Clark 3, Megan Hannon 1 and Jonathan M. Mansbach 1 1 Department of Medicine, Children’s Hospital Boston, Harvard Medical School, 300 Longwood AvCe, Boston, MA 02115, USA; E-Mails: Megan.Hannon@ (M.H.); Jonathan.Mansbach@ (J.M.M.) 2 Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, 326 Cambridge St, Suite 410, Boston, MA 02114, USA; E-Mail: ccamargo@ 3 Department of Medicine, University of Pittsburgh, 200 Meyran Avenue, Suite 300, Pittsburgh, PA 15213, USA; E-Mail: Sunday.Clark@ * Author to whom correspondence should be addressed; E-Mail: Amanda.Growdon@; Tel.: +1-617-355-4993; Fax: +1-617-730-0884. Received: 1 December 2011; in revised form: 29 February 2012 / Accepted: 5 March 2012 / Published: 16 March 2012 Abstract: As indoor workers, trainee doctors may be at risk for inadequate vitamin D. All trainee doctors (residents) in a Boston pediatric training program (residency) were invited to complete a survey, and undergo testing for serum 25-hydroxyvitamin D [25(OH)D], PTH, and calcium during a 3-week period in March 2010. We examined the association between resident characteristics and serum 25(OH)D using Chi2 and Kruskal-Wallis test and multivariable linear and logistic regression. Of the 119 residents, 102 (86%) participated. Although the mean serum 25(OH)D level was 67 nmol/L (±26), 25 (25%) had a level 50 nmol/L and 3 (3%) residents had levels 25 nmol/L. In the multivariable model, factors associated with 25(OH)D levels were: female sex (β 12.7, 95% CI 3.6, 21.7), white race (β 21.7, 95% CI 11.7, 31.7), travel to more equatorial latitudes during the past 3 months (β 6.3, 95% CI 2.0, 10.5) and higher daily