Some Heteroaromatic Organomercurials, Their Syntheses and Reactions A Review of Our Research (1980-2000) 英文参考文献.docVIP

Molecules 2001, 6, 927-958 molecules ISSN 1420-3049 Review Some Heteroaromatic Organomercurials, Their Syntheses and Reactions: A Review of Our Research (1980-2000) Lech Skulski* and Piotr Wroczynski* Chair and Laboratory of Organic Chemistry (L.S.) and Department of Physical Chemistry (P.W.), Faculty of Pharmacy, Medical University, PL 02-097 Warsaw, Poland, Banacha 1. Tel./Fax: +(48) 22-8226843. *To whom the correspondence should be addressed; E-mail: lskulski@.pl or wropio@.pl Received: 1 October 2001 / Accepted 24 October 2001 / Published: 30 November 2001 Abstract: This review reports some novel (or improved) synthetic methods for preparing a number of aromatic (carbocyclic and predominantly heterocyclic) organomercurials, particularly those derived from theophylline, theobromine and uracil, as well as some novel halo- and cyano-demercuration reactions. We have also synthesized the first stable organic derivative of mercury(I), viz. 1,8-bis(acetoxy- dimercurio)theobromine, and studied its novel reactions. We have also improved the old Willgerodt method (1897), applicable for preparing various diaryliodonium chlorides from appropriate (dichloroiodo)arenes and symmetric aromatic mercurials. A full list of our works, published over the past twenty years (1980-2000), is also provided (see Refs. 1-16). Keywords: heteroaromatic organomercurials, halo-demercuration reactions, cyano- demercuration reaction, heteroaromatic halides and nitriles  Molecules 2001, 6 928 Contents 1. Introduction 2. Early Results: 8-Substituted Caffeine Mercurials and Their Demercuration Reactions 2.1. Halo-demercuration Reactions of Caffeine Mercurials 2.2. Cyano-demercuration Reaction of Caffeine Mercurials 2.3. Unsuccessful Reactions with Caffeine Mercurials and Conclusions 3. Model Monosubstituted Benzene Mercurials and Their Demercuration Reactions 4. Model 2-Substituted Furan and Thiophene Mercurials and Their