Surface pretreatments for medical application of adhesion 英文参考文献.docVIP

BioMedical Engineering OnLine BioMedCentral Review Open Access Surface pretreatments for medical application of adhesion Hans J Erli?2, Rudolf Marx*?1, Othmar Paar2, Fritz U Niethard3, Michael Weber?1 and Dieter C Wirtz?3 Address: 1Department of Prosthetic Dentistry, Section of Dental Materials, University Hospital of the University of Technology, Aachen, Germany, 2Department for Trauma Surgery, University Hospital of the University of Technology, Aachen, Germany and 3Department of Orthopedic Surgery, University Hospital of the University of Technology, Aachen, Germany Email: Hans J Erli - herli@ukaachen.de; Rudolf Marx* - marx@rwth-aachen.de; Othmar Paar - opaar@ukaachen.de; Fritz U Niethard - funiethard@orthopaedie-aachen.de; Michael Weber - mail@michaelweber.de; Dieter C Wirtz - dcwirtz@ukaachen.de * Corresponding author ?Equal contributors Published: 18 September 2003 Received: 18 March 2003 Accepted: 18 September 2003 BioMedical Engineering OnLine 2003, 2:15 This article is available from: /content/2/1/15 ? 2003 Erli et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the articles original URL. Abstract Medical implants and prostheses (artificial hips, tendono- and ligament plasties) usually are multi- component systems that may be machined from one of three material classes: metals, plastics and ceramics. Typically, the body-sided bonding element is bone. The purpose of this contribution is to describe developments carried out to optimize the techniques , connecting prosthesis to bone, to be joined by an adhesive bone cement at their interface. Although bonding of organic polymers to inorganic or organic surfaces and to bone has a long history, there remains a serious obstacle in realizing long-term high-bonding strengths in the in vivo body environment