Vasopressin improves outcome in out-of-hospital cardiopulmonary resuscitation of ventricular fibrillation and pulseless ventricular tachycardia a observational cohort study 英文参考文献.docVIP

Available online /content/10/1/R13 Research Open Access Vol 10 No 1 Vasopressin improves outcome in out-of-hospital cardiopulmonary resuscitation of ventricular fibrillation and pulseless ventricular tachycardia: a observational cohort study Stefek Grmec1 and Stefan Mally2 1Assistant Professor, Head of the Department, Centre for Emergency Medicine Maribor, University of Maribor, Maribor, Slovenia 2Medical Doctor, Centre for Emergency Medicine Maribor, Maribor, Slovenia Corresponding author: Stefan Mally, stefan.mally@ Received: 3 Aug 2005 Revisions received: 24 Oct 2005 Accepted: 12 Dec 2005 Published: 6 Jan 2006 Critical Care 2006, 10:R13 (doi:10.1186/cc3967) This article is online at: /content/10/1/R13 ? 2006 Grmec and Mally; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction An increasing body of evidence from laboratory and clinical studies suggests that vasopressin may represent a promising alternative vasopressor for use during cardiac arrest and resuscitation. Current guidelines for cardiopulmonary resuscitation recommend the use of adrenaline (epinephrine), with vasopressin considered only as a secondary option because of limited clinical data. restoration of spontaneous circulation and subsequent hospital admission were higher in vasopressin-treated groups (23/53 [45%] in group I, 19/31 [61%] in group II and 17/27 [63%] in group III). There were also higher 24-hour survival rates among vasopressin-treated patients (P 0.05), and more vasopressin- treated patients were discharged from hospital (10/51 [20%] in group I, 8/31 [26%] in group II and 7/27 [26%] group III; P = 0.21). Especially in the subgroup of patients with myocardial infarction as the underlying cause