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Characterization of chronic HCV infection-induced apoptosis
Zekrietal.ComparativeHepatology2011,10:4
/content/10/1/4
RESEARCH
OpenAccess
CharacterizationofchronicHCVinfection-induced
apoptosis
Abdel-RahmanNZekri1*,AbeerABahnassy2,MohamedMHafez1,ZeinabKHassan1,MahmoudKamel3,
SamahALoutfy1,GhadaMSherif4,Abdel-RahmanEl-Zayadi5andSayedSDaoud6
Abstract
Background:Tounderstandthecomplexandlargelynotwell-understoodapoptoticpathwayandimmunesystem
evasionmechanismsinhepatitisCvirus(HCV)-associatedhepatocellularcarcinoma(HCC)andHCVassociated
chronichepatitis(CH),westudiedtheexpressionpatternsofanumberofpro-apoptoticandanti-apoptoticgenes
(Fas,FasL,Bcl-2,Bcl-xL
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