Effects of particulate air pollution on blood pressure in a highly exposed population in Beijing, China a repeated-measure study.docVIP
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Effects of particulate air pollution on blood pressure in a highly exposed population in Beijing, China a repeated-measure study
Baccarellietal.EnvironmentalHealth2011,10:108
/content/10/1/108
RESEARCH
OpenAccess
Effectsofparticulateairpollutiononblood
pressureinahighlyexposedpopulationin
Beijing,China:arepeated-measurestudy
AndreaBaccarelli1,FrancescoBarretta2,ChangDou3*,XiaoZhang4,JohnPMcCracken1,AnaitéDíaz5,
PierAlbertoBertazzi2,JoelSchwartz1,ShengWang6andLifangHou4
Abstract
Background:ParticulateMatter(PM)exposureiscriticalinBeijingduetohighpopulationdensityandrapid
increaseinvehiculartraffic.PMeffectsonbloodpressure(BP)havebeeninvestigatedasamechanismmediating
cardiovascularrisks,butresultsarestillinconsistent.Thepurposeofourstudyistodeterminetheeffectsof
ambientandpersonalPMexposureonBP.
Methods:Beforethe2008OlympicGames(June15-July27),weexamined60truckdriversand60officeworkers
ontwodays,1-2weeksapart(n=240).Weobtainedstandardizedmeasuresofpost-workBP.Exposureassessment
includedpersonalPM2.5 andElementalCarbon(EC,atraceroftrafficparticles)measuredusingportablemonitors
duringworkhours;andambientPM10 averagedover1-8dayspre-examination.Weexaminedassociationsof
exposures(exposuregroup,personalPM2.5/EC,ambientPM10)withBPcontrollingformultiplecovariates.
Results:MeanpersonalPM2.5 was94.6μg/m3(SD=64.9)inofficeworkersand126.8(SD=68.8)intruckdrivers
(p-value0.001).Inallparticipantscombined,a10μg/m3increasein8-dayambientPM10 wasassociatedwithBP
incrementsof0.98(95%CI0.34;1.61;p-value=0.003),0.71(95%CI0.18;1.24;p-value=0.01),and0.81(95%CI0.31;
1.30;p-value=0.002)mmHgforsystolic,diastolic,andmeanBP,respectively.BPwasnotsignificantlydifferent
betweenthetwogroups(p-value0.14).PersonalPM2.5 andECduringworkhourswerenotassociatedwith
increasedBP.
Conclusions:OurresultsindicatedelayedeffectsofambientPM10 onBP.Lackofassociationswithexposure
groupsandpersonalPM2.5/ECindicatesthatPMeffectsarerelatedtobackgroundlevelsofpollutioninBeijing,and
notspecificallytowork-relatedexposure.
Keywords:ParticulateMatter,PersonalMonitoring,BloodPressure,TrafficPollution,China
Background
withtheseacutec
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