2006～2008年鲍曼不动杆菌的耐药性变迁.pdfVIP

检验医学与l临床 2009 年 11 月第 6 卷第 21 期 Lab Med Clin. November 2009. Vo l. 1l .No. 21 • 1801 • 2006~2008 年鲍曼不动杆菌的耐药性变迁 朱晓华，林青青(重庆市第三人民医院 400014) E摘要E 目的 了解 2006 年 1 月至 2008 年 12 月重庆第三人民医院鲍曼不动杆菌的耐药变迁，为临床合理应 用抗菌药物提供依据。方法 采用美国 DADE 公司的 MicroscanAutoscan-4 型微生物分析仪对细菌进行鉴定并做 药敏试验。结果 碳青霉烯类抗菌药物是所有被测药物中对 178 株鲍曼不动杆菌抗菌作用最强的抗菌药物，但亚 接培南的耐药率在 2008 年已达 4 1. 2%。鲍曼不动杆菌多重耐药严重，对临床常用抗菌药物的耐药性呈逐年上升 趋势。结论 应加强鲍曼不动杆菌耐药性监测，了解其耐药变迁，指导临床合理用药，防止耐药菌株的传播。 E关键词E 鲍受不动杆菌$ 耐药变迁F 防治对策 中国分类号:R969.4 文献标志码:A 文章编号:1672-9455(2009)21-1801-02 Changes of antimicrobial resistance among acinetobacter baomannii isolated from the patients in the year of 2006 to 2008 ZHU Xia o-hua .LIN Qing-qing. The Third Peoρle￥ Hosρital of Chongqing 400014 Chongqing China (Abstract] Objective To analyze the trend of infections and the antibiotic resistance of acinetobacter bauman nii in Chongqing Third People s Hospital during 1an. 2006 to Des. 2008Methods Bacterial pathogens were identified and detected by Microscan Autoscanne r-4. and vitro antibiotic resistance of all the isolates from our hospital was studied. Results Although carbapenems were the most active antibiotics tested agaínst acinetobacter baumannii. 4 1. 2% of acinetobacter baumannii in 2008 was resistance to imipenem. Susceptibility test showed that acÏnetobacter baumannii was multiple resistance. The antimicrobial resistance of acinetobacter baumannii increased. . Conclosion Monitoring of the antimicrobial resistance to acinetobacter baumannii should be strengthened. The change of the anti- microbial resistance should be investigated for rational drug use in the clinic and prevent bacterial strain of drug re- sistance from being transmitted. (Key Words] acinetobacter baumannii; drug resistanc; strategy 鲍曼不动抒菌是一种不发酵糖、氧化酶阴性、动力阴性的 对 13 种抗陶药物的耐药情况见表