鼻咽癌继发上矢状窦转移病例报道及文献分析.pdfVIP

外科研究与新技术 20l3 年3月第2卷第l期 27 Superiorsagittalsinusmetastasisfrom nasopharyngeal carcinoma :a casereportandreviewofliterature HAI ian, SUShaO-hua, YUfei, WUYi-fang DepartmentofNeurosurgery,TongjiHospitai,Tongjiuniversityschooiofmedicine,shanghai 200065,china Abstract]Nasopharyngeaicarcinoma(NPc) isoneofthemostcommon maiignanciesin thehead and neck, especiaiiyamongchinesepopuiation.AithoughNPchasapropensitytodeveiopdistantmetastasesatahighrateinciuding bones,iungs,iiveranddistantiymphnodes,superiorsagittaisinusmetastasesfromNPcareveryrare.wereportacaseof suchadiseaseina54-year-oidmanwithNPcwhopresentedwithheahache,vomitingandstatusepiiepticus24monthsafter finishingradiotherapyandchemotherapy.mRishowedthepresenceofaoccupyingiesioninrightfrontaiiobeassociatedwith superiorsagittaisinus,which wasinitiaiiymisdiagnosed asaparasagittaimeningioma.Thepatientreceived surgicai treatmentviacraniotomy.Histoiogicandimmunohistochemicaianaiysesconfirmedthatitwasoriginainasopharyngeai.After resectionoftheintracraniaitumors,nosignsofiocaiordistantrecurrencewasnotedduringthe6monthsfoiiowup.Aithough surgicaitreatmentpiaysaiimited roiein metastaticNPc,thereisrarecasesofintracraniaisinusmetastasiswith a reasonabieoutcomeafterresections. Key words]Nasopharyngealcarcinoma; Superiorsagittalsinus; Metastasis; Surgery 鼻咽癌继发上矢状窦转移病例报道及文献分析 海 舰# 苏少华# 余 飞#吴一芳 同济大学附属同济医院神经外科,上海 200065 #摘 要$ 鼻咽癌是国人头颈区域常见的恶性肿瘤之一,尽管鼻咽癌容易发生远处转移,包括骨骼~肺部~肝脏 和远处淋巴结等部位,但继发于鼻咽癌的上矢状窦部位转移十分罕见 我们首次报道一例54岁鼻咽癌男性患者, 该患者于放疗和化疗后24个月出现头痛~呕吐~癫痫发作,头颅MRI检查发现右侧额叶占位,肿瘤基底与矢状窦关 系密切,临床初步诊断为窦旁脑膜瘤 患者接受了开颅手术治疗,术后组织学和免疫组化结果显示为鼻咽癌,术后 随访6个月,患者未再出现局部或远处转移征象 尽管手术切除转移性鼻咽癌并不提倡,但