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Asian Case Reports in Vascular Medicine 亚洲心脑血管病例研究, 2016, 4(2), 7-13
Published Online May 2016 in Hans. /journal/acrvm
/10.12677/acrvm.2016.42002
The Relationship and Possible
Mechanism between Patent
Foramen Ovale and Migraine
with Aura
1 2 2* 2* 2 2
Cai Liu , Gesheng Chen , Fenling Fan , Yushun Zhang , Lu He , Xingye Wang ,
Yuliang Zou3 1 1
, Xiao Zhao , Mingzhen Zhu
1
Medical School, Xi’an Jiaotong University, Xi’an Shaanxi
2
Department of Cardiology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an Shaanxi
3
Department of Gynaecology and Obstetrics, The First Affiliated Hospital of Xi’an Jiaotong University,
Xi’an Shaanxi
th th th
Received: Jun. 4 , 2016; accepted: Jun. 24 , 2016; published: Jun. 27 , 2016
Copyright © 2016 by authors and Hans Publishers Inc.
This work is licensed under the Creative Commons Attribution International License (CC BY).
/licenses/by/4.0/
Abstract
The incidence of patent foramen ovalen is 1/4 among normal people; more and more data show
that patent foramen ovale is correlated with stroke, migraine and other clinical disease in re-
cent years. At present, some studies have found that patent foramen ovale is closely related with
migraine with aura, mainly considered that some chemicals went into the brain circulation by
the open way of patent foramen ovale which induced migraine attack. Due to the serious damage
of physical and mental health of the migraine, bad quality of life and work productivity, an
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