品行障碍青少年静息态脑功能局部一致性研究_王朋朋.pdfVIP

210 2011 03 19 3 CJ CHC MAR. 2011, Vol 19, No. 3 : 1008-6579( 2011) 03-0210- 04 = 品行障碍青少年静息态脑功能局部一致性研究 1 1, 2 2 1 王朋朋 , 张劲松 , 夏卫萍 , 廖祥鹏 ( 1 上海交通大学医学院附属新华医院儿童与青少年保健科, 上海市环境与儿童健康重点实验室, 上海 200092; 2 上海交通 大学医学院附属新华医院临床心理科, 上海 200092) : R749. 94 : A : = 目的 ( conduct disorder, CD) = 方法 12 DSM-IV 12~ 18 11 , ( ReH o) , CD = 结果 , , CD ReH o , ReH o = 结 论 , , : 品行障碍; 磁共振成像; 局部一致性 Regional homogeneity in the patients with conduct disorder: a resting- state functional magnetic resonance imaging study. 1 1, 2 2 1 WA NG Peng-p eng , ZH A NG J in-song , X IA Wei-p ing , LIA OX iang-p eng . ( 1 Dep artment of Child and Adolescent Health Care, Xinhua Hospital Af f iliated to Shanghai Jiaotong University , School of Medicine, Shanghai Institute f or ediatric Research, Shanghai Key Laboratory of Childrens Environmental Health, Shanghai 200092, China; 2 Depart- ment of Medical sy chology , Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200092, China) Abstract: =Obj ective T o investigate the differences of brain spontaneous activit in rest ing state betw een adoles- cents wit h conduct disorder ( CD) and matched controls using function magnetic imaging (fM RI) . = Method 11 cases d-i agnosed w ith DSM-IV and 11 normal controls underw ent resting-state fMRI, the data w ere anal zed using a new l reported met hod called Regional H omogeneit ( ReH o) to anal ze fMRI data betw een CD and normal cont rols. = Result Compared with normal controls, CD showed decreased ReH o in bilateral front al lobe and left inferior