复方五仁醇胶囊保肝作用的血清药理学研究论文.docVIP

　　复方五仁醇胶囊保肝作用的血清药理学研究论文 作 者：张兵，窦志华，罗 琳，达坤林，尤蝠仪，曹卫菊 【摘要】 目的：建立复方五仁醇胶囊血清药理学研究方法。方法：建立CCl4诱导的原代培养大鼠肝细胞损伤模型，大鼠为含药血清供体，以含药血清对损伤肝细胞增殖（MTT法）及丙氨酸氨基转移酶（ALT）泄漏的影响两个指标.freel pharmacology testing method for pound ary culture hepatocyte containing CTT),.freelinotransferase(ALT) in cell culture medium and the content of schisandrin in serum as indices, single-factor investigation and multiple-factor orthogonal experiment or plasma, and serum containing drug in culture system of different concentration on pharmacological effect and to screen of the preparative method of serum containing drug and its suit