龙游萎鼻讲座.pptVIP

Atrophic Rhinitis and its Control（猪萎缩性鼻炎及其控制）—ARadicatorTM（克伟?） 钱卫东 Atrophic Rhinitis – Disease and Methods Outline: Brief overview of Atrophic Rhinitis – the disease and associated organisms Diagnosis Epidemiology Control Methods of Assessing Atrophic Rhinitis Atrophic Rhinitis （萎缩性鼻炎）– Disease（疾病） Two Forms of Atrophic Rhinitis Non-Progressive, uncomplicated Bordetella bronchiseptica, toxigenic Mild Turbinates recover Progressive Pasteurella multocida, toxigenic, usually Type D Toxin is the active factor in causing atrophy Mild to severe remodeling of turbinates and bony structure of the nose Lesion progresses in absence of detectable organisms in the nasal cavity Atrophic Rhinitis （萎缩性鼻炎）– Disease（疾病） Progressive Atrophic Rhinitis Severity is variable – Depends on: Age of pig (younger are more susceptible) Amount of toxin (P. multocida) Other irritants promoting colonization of toxigenic P. multocida B. bronchiseptica (natural conditions) Acetic acid (experimental conditions) Air quality? Atrophic Rhinitis – Disease Economics Estimates of prevalence range from 20% to 80% Economic loss due to: Poor Growth Poor Feed Conversion Increased medication costs Uneven lots for slaughter Progressive Atrophic Rhinitis – Diagnosis Clinical Signs Distorted, blunted, twisted nose Sneezing with Mucus or bloody noses Poor growth (other complicating factors?) Slaughter Check Examine snout cut at level of 2nd premolar tooth Distortion of turbinates Loss of bony structure in turbinates Distortion of septum Pneumonia Recovery of organisms from swabs Nasal Tonsil Serology Progressive Atrophic Rhinitis – Epidemiology Horizontal Transmission From introduced carrier pigs to susceptible penmates Vertical Transmission From carrier sows to susceptible offspring Progressive Atrophic Rhinitis – Control Control sources of infections Early weaning with medication Antibiotics in Sow’s Gestation Feed Injectable for suckling pigs (repeated doses) Antibiotic treatment in older pigs may limit