原创力文档- 1、本文档共50页，可阅读全部内容。
- 2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
- 3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
查看更多
英文 溶血性贫血(徐运孝)
一、General Information ● Hb Structure ● Definition of Hemolytic Anemias 3、Pathogenesis Intrinsic abnormities of red cells: red cell membrane disorders ；enzyme defects ；hereditary Hb disease. Extrinsic abnormities of red cells: Immune；Physical and mechanical； chemical；infections。 四、Diagnosis （一）Dominant evidence of diagnosis 1、Clinical manifestations of hemolytic anemia 2、Laboratory examinations show the life span of red cells is shortened and the destruction of red cells is excessive. 3、Significant increase of normoblast hyperplasia in bone marrow (1)examination about the shortened life span and excessive destruction of the red cells. ? The life span of the red cells is shortened. 32P-DFP or H-DFP T1/2?15 d (normal 25-32d) ? changes of red cell morphology:spherocyte,ellipotocyte,stomatocyte,helmet cell,sickle cell. ? LDH ?? （2）Examination about the increased plasma free hemoglobin moderate hemolysis combine with Hp Hp ? small part combine with hemopexin hemopexin? free Hb ? albumin severe hemolysis some convert to methemoglobin methemalbumin renal reabsorption epithlium major port hemoglobinuria by renal tubule urine hemosiderin hemosiderineuria desquamation （3）Examination about abnormal metabolism of bilirubin Indirect bilirubin? Urine urobilinogen?，urine bilirubin（-） Stool bilinogen? （三）Find the etiology of hemolysis anemia ? Exam
文档评论（0）