TPPA 阳性TRUST阴性新生儿临床处理探析.docVIP

TPPA 阳性TRUST阴性新生儿临床处理探析【中图分类号】R473.72 【文献标识码】B 【文章编号】1672－3783(2011)12－0071－01 【摘要】目的：探讨TPPA及TRUST均阳性的产妇所生TPPA阳性TRUST阴性的新生儿是否需要驱梅治疗。方法：将154例TPPA阳性TRUST阴性新生儿（产妇TPPA及TRUST均阳性），产妇产前未经正规治疗113例随机分为两组，新生儿给予驱梅治疗的为治疗组(60例)，不给予驱梅治疗的为对照1组（53例）。产妇产前经青霉素正规治疗的41例为对照2组。观察各组TPPA转阴情况。结果：3个月TPPA各组转阴率分别为18.33%、16.98%、17.07%。6个月分别为100%、98.1%、100%。12个月分别为100%、98.1%、100%。12个月时发现对照1组TPPA未转阴的那例新生儿TRUST也出现阳性滴数为1:2。结论：1.对未经治疗梅毒产妇所生TPPA阳性TRUST阴性的新生儿应密切观察其TPPA变化至少18个月。因先天梅毒对新生儿危害极大如有条件都可以给予驱梅治疗。2.妊娠前和妊娠期均经青霉素正规治疗的梅毒产妇所生TPPA阳性TRUST阴性的新生儿基本能排除先天潜伏梅毒 【关键词】产妇，先天潜伏梅毒，新生儿 Clinical Analysis of the Neonates of with Positive TPPA and Negative TRUST Hengkun， liyingchun yang tangling， hegongjian， 【Abstract】Objective To investigate if the neonates of syphilis female with positive TPPA and positive TRUST, whose TPPA is positive and TRUST is negative, should receive out-syphilis treartment. Methods 154 neonates of syphilis female with positive TPPA and positive TRUST were devivided into two groups, according the pregnant and unpregnant women were treated or untreated. the neonates of receiving treatment was control group, and the neonates of receiving untreatment was observation groupI. the neonates of receiving treatment during pregnant and unpregnant was observation group II. The efficency of every groups during treatment were observed. Results After three months the negative rates of TPPA were 18.33%、16.98%、17.07% respectively in control group, observation group I , group II. And after six months the negative rates of TPPA were 100%、98.1%、100% respectively in control group, observation group I, group II. after twelve months the negative rates of TPPA were 100%、98.1%、100% respectively in control group, observation group I and group II in turn. In twelve months, the neonates of TRUST titre was1:2 in control group. Conclusion The neonates of untreated syphilis female with positive TPPA and positive TRUST, whose TPPA is positive and TRUST is negative, should receive out-syphilis treartment for