补佳乐和安宫黄体酮用于药物流产不全的临床观察.DOCVIP

补佳乐和安宫黄体酮用于药物流产不全的临床观察 周良燕 浙江省嵊州市中医院，浙江 嵊州 312400 【摘要】目的：观察补佳乐和安宫黄体酮用于药流不全的临床效果。方法：在药物流产后阴道流血时间15天，血HCG1600U/L,B超检测残留物2cm者，观察组每天口服补佳乐片1mg*10天，后5天加每天加服安宫黄体酮片10mg。对照组肌注催产素针10u*3天，同时口服益母草冲剂20g 2次/日*7天。进行临床疗效比较。结果：观察组治愈率为71.15%，对照组治愈率28.85%，二组经统计学检验有显著性差异（P0.01),观察者的效果优于对照组。结论：补佳乐和安宫黄体酮在治疗药流不全时疗效显著，并具有安全，无痛苦的优点。 【关键词】药流不全；补佳乐；安宫黄体酮；保守治疗 Observation on effect of progynova and depogeston in the Treatment of incomplete Drug Abortion [ Abstract ] Objective: To estimate the effectiveness of the progynova and depogeston in individuals after incomplete drug abortion. Methods: this study was performed at two groups with vaginal bleeding after drug abortion for 15 days, blood HCG 1600U / L and B ultrasound test identified the residues 2cm. Experimental group daily oral progynova 1mg for 10 days, plus daily oral depogeston tablets 10mg in the last 5 days, control group were daily intramuscular injection of oxytocin needle 10u for 3 days, while oral Yimucao on 20g twice daily for 7 days. Results: The cure rate in the experimental group was 90.38%, compared to the control group the cure rate was 28.84%, with significant difference ( P 0.01 ) of statistical test and more effectiveness. Conclusion: progynova and depogeston in the treatment of incomplete medical abortion is effective with advantages of safety and painless. [ Key words ] incomplete drug abortion; progynova; depogeston; conservative treatment 药物流产自问世以来以其痛苦小，非侵入性的独到优势迅速被一些早孕妇女接受终止妊娠的一种手段。但药物流产后阴道流血时间长，出血较人流术后多，1有资料表明，药物流产约存在有5%左右药流不全，在一定程度上影响了药物流产术的顺利开展，成为困扰着医患双方的一大难题，是目前亟待解决的问题。药物流产不全传统解决方法采用清宫术，我院应用补佳乐片配伍安宫黄体酮片对于药流不全病例保守治疗上取得了较好的临床效果，现报道如下。 1.资料和方法 1.1一般资料 2002年1月-2005年8月因药物流产后半月阴道流血不止在本院门诊就诊，药流时见孕囊排出，经B超检查确诊为药流不全病人。入选条件：①血常规检查Hgb110g/L，白细胞正常；②血HCG1600U/L；③阴道流血量明显少于月经数量；④妇检排除宫颈口组织堵塞及盆腔炎症；⑤排除肿瘤；⑥B超检查宫腔内见直径小于2cm不均质回声或子宫内膜毛超厚12mm，不均质回声团块内或见血流信号；⑦排除补佳乐禁忌症；⑧能够密切配合随访，服药前告知服药的利弊及不良反应。患者自愿采取保守治疗，选择年龄在25+/-3岁，共104例。随机分为观察组及对照组各52例。 1.2 治疗方法 所有病例均予以预防感染治疗。观察组每天口服补佳乐片1mg*10天，后5天加每天加服安宫黄体酮片10mg。对照组肌注催产素针10u*3天