ICU内高钠血症患者采用连续血液净化治疗疗效观察.pdfVIP

国际医药卫生导报2015 年第21 卷第22 期 IMHGN , Novemher 2015 , Vo1.21 No.22 ICU 内高纳血症患者采用连续血液净化 治疗疗效观察 许治本 [摘要] 目的 观察连续血液净化治疗 ICU 内高铀血症患者的临床疗效。方法 96 例 ICU 内高铀血症患者按照治疗方式不同分为对照组与治疗组各48 例。对照组采用常规保守治疗，治疗 组于对照组治疗基础上采用连续血液净化治疗。观察两组患者治疗前后血铀浓度、肌哥、尿素氮、 血浆渗透压、心率、平均动脉压变化，预后。结果 治疗后，两组患者血铀浓度、肌膏、尿素氮、 血浆渗透压较治疗前均明显下降，但治疗组下降更显著(P 0.05); 两组患者平均动脉压较治疗前 均明显升高，但治疗组升高更显著 (p 0.05)。随访 1 年，治疗组分别治愈及存活 22 例 (45.83%) 、 43 例(89.5813吟，明显高于对照组的 13 例。7.08%) 、 31 例(64.5813份，差异有统计学意义(x 2 = 6.75 , 8.9~ P 0.05)。结论 临床采用连续血液净化治疗ICU 内高铀患者，可显著降低其血铀浓度，并有效改 善其肾功能及血浆渗透压，逐步稳定其生命体征，提高临床疗效，从而改善预后。 [关键词] 高铀; ICU; 连续血液净化 Effect of continuous blood purification on patients with hypernatronemia in ICU Xu Zhiben. IC U, The Peoples Hospital 01Dingan Coun秒: Dingan 571200, China [ Abstract 1 Objective To observe the clinical effect of continuous blood purification in the treatment of patients with hypematronemia in ICU. Methods 96 patients with hypematronemia in ICU were divided into control group and treatment group , 48 cases in each group. Control group was treated with conventional conservative treatment, and treatment group was treated with continuous blood purification on the basis of control group. Observed blood sodium concentration, creatinine, urea nitrogen , plasma osmotic pressure , heart rate , mean arterial pressure before and a负er treatment, prognosis of two groups. Results After treatment, serum sodium concentration, creatinine, urea nitrogen , plasma osmotic pressure of two groups decreased, and tbose of treatment group decreased more significantly (P0.05); mean arterial pressure of two groups increased, and that of treatment group increased more significantly (P0.05). The cure rate and the survival rate of treatment group were 45.83% , 89.58% respectively, significantly higher than 27.08%, 64.58% of control group, with statistically significant differences (P0.05)