儿童青少年体成分影响因素的双生子研究.pdfVIP

主旦芏 墨 墨生 旦箜 鲞箜 塑．Chin J Seh Health，April 2008，Vo1．29，No．4 295 【生长发育与健康状况】 儿童青少年体成分影响因素的双生子研究 何鲜桂 ，季成叶 ，李玉玲 ，张悦 ，熊敏 ，陈天娇 【摘要】 目的 分析儿童青少年体成分发育指标的遗传度，探讨遗传对儿童青少年体成分发育的影响。方法 测量603对6～18岁 同性别双生子(单卵双生431对，二卵双生172对)的体重、肱三头肌皮褶厚度、肩胛下皮褶厚度，计算2处皮褶厚度之和、体脂率、体脂量和 瘦体重。用组内相关系数法，计算调整年龄后各指标遗传度。结果 各指标组内相关系数均为单卵双生子大于二卵双生子，遗传度均在 0．72以上，性别差异无统计学意义。体脂率遗传度男为0．77，女为0 73；体脂量男为0．79，女为0．78；瘦体重男为0．87。女为0．86。结论 遗传因素对儿童青少年体成分发育起主要控制作用，其影响程度无明显的性别差异。 【关键词】 身体成分；因素分析，统计学；双生研究；青少年 【中图分类号】 R】79 R 339．3 5 【文献标识码】 A 【文章编号】 1000-9817(2008)04-0295-03 Twin Study on the Influencing Fado~to Body Composition of Children and Adolescents／HE Xian-gui ， Cheng-ye。LI Yu-ling。et a1． Institute ofChild amt Adolescent Health。Peking Universi0。Beifing(100083)。China 【Abstract】 Objective To analyze the heritability of body composition indices in children and adolescents。and to explore the effect of heredi· ty on children and adolescents body composition．Me~ods A total of603 twin pairs-431 monozygotic(MZ)and 172 dizygotic(DZ)aged 6 to 18 yeats，were investigated．rrhe measurement included weisht，triceps skinfold and subscapular skinfold，Sum of triceps and subscapular skinfolds，per- centage of body fat(PBF)，total of body fat(TBF)and lean body mass(LBM)were caculated．1The heritabilities were estimated using intracla~cor- relation coefficient method from the adjusted data for age．Results rrhe intraclass correlation coefficient Was hig}ler in the MZ twins than in the DZ twins，the heritabilities were all above 0．72。and there were nO statistical significant differences of sex betwecn them．1The heritabilities of PBF were 0．73 in female。0．77 in male。fl0r TBF were 0．78 and 0．79。for LBM were 0．86 and 0．87．Conclusion Heredity plays a dominant role i11 the growth and developmen