夫西地酸钠联合磷霉素钠治疗MRS感染的临床疗效观察.pdfVIP

636 中国抗生素杂志2013年08月第38卷第8期 夫西地酸钠联合磷霉素钠治疗MRS感染的临床疗效观察 何文富 (宜宾市第一人民医院药剂科，宜宾644000) 摘要：目的 评价夫西地酸钠联合磷霉素钠治疗耐甲氧西林葡萄球菌(MRs)院内感染的疗效性和安全性。方法回顾性分 析我院3年来临床夫西地酸钠联合磷霉素钠治疗耐甲氧西林葡萄球菌院内感染的265例患者的临床资料。数据资料采用SPSSl3．0 静脉炎，发生率为7．5％。结论 夫西地酸钠联合磷霉素钠治疗耐甲氧西林葡萄球菌感染安全、有效，临床可根据患者感染的具 体状况选择夫西地酸钠联合磷霉素钠优化治疗。 关键词：夫西地酸钠；磷霉素钠；耐甲氧西林葡萄球菌 中图分类号：R978．1文献标志码：A Clinicalevaluationof sodiumfusidateand combining sodium for MRSinfection fosfomycintreating HeWen．fu of First (DepartmentPharmacy,the ofYibin，Yibin644000) People’SHospital AbstractectiveToevaluatethe and of sodiumfusidateandsodium Obj efficacysecuritycombining inthetreatmentof methicillin．resistant infection．Methods265 fosfomycin hospitalacquired staphylococci(MRSl MRSinfectionwhotreatedwith sodiumfusidateandsodium were hospitalacquired patients combining fosfomycin thedatainformation were SPSS13．0．measurementdatawere t analyzed．A1l processedbyusing analyzedbytesting． betweenwere differenceiS when 72test，the significant comparisongroupsanalyzedby statistically From 2009toDecember20 were1 methicillin．resistant January 11，there 39(52．5％1 StaphyloCOCCUS and1 resistant 265 MRSinfection 26(47．5％)methicillin Staphy-lococcusepidermidis(MRSE)inhospitalacquired wh